Synthetic chromosomes, genomes, viruses, and cells

JC Venter, JI Glass, CA Hutchison, S Vashee - Cell, 2022 - cell.com
Synthetic genomics is the construction of viruses, bacteria, and eukaryotic cells with
synthetic genomes. It involves two basic processes: synthesis of complete genomes or …

Chromosome Transplantation: Opportunities and Limitations

A La Grua, I Rao, L Susani, F Lucchini, E Raimondi… - Cells, 2024 - mdpi.com
There are thousands of rare genetic diseases that could be treated with classical gene
therapy strategies such as the addition of the defective gene via viral or non-viral delivery or …

Mitotic drive in asymmetric epigenetic inheritance

R Ranjan, X Chen - Biochemical Society Transactions, 2022 - portlandpress.com
Asymmetric cell division (ACD) produces two daughter cells with distinct cell fates. This
division mode is widely used during development and by adult stem cells during tissue …

Engineering better artificial chromosomes

RK Dawe - Science, 2024 - science.org
Artificial chromosomes can carry large numbers of engineered genes and have been
proposed as an alternative technology for adding or recoding genetic information in human …