PTML multi-label algorithms: models, software, and applications

B Ortega-Tenezaca, V Quevedo-Tumailli… - Current Topics in …, 2020 - ingentaconnect.com
By combining Machine Learning (ML) methods with Perturbation Theory (PT), it is possible
to develop predictive models for a variety of response targets. Such combination often …

Risk assessment of veterinary drug residues in meat products

H Zhang, Q Chen, B Niu - Current Drug Metabolism, 2020 - ingentaconnect.com
With the improvement of the global food safety regulatory system, there is an increasing
importance for food safety risk assessment. Veterinary drugs are widely used in poultry and …

Designing nanoparticle release systems for drug–vitamin cancer co-therapy with multiplicative perturbation-theory machine learning (PTML) models

R Santana, R Zuluaga, P Gañán, S Arrasate, E Onieva… - Nanoscale, 2019 - pubs.rsc.org
Nano-systems for cancer co-therapy including vitamins or vitamin derivatives have showed
adequate results to continue with further research studies to better understand them …

PTML model for selection of nanoparticles, anticancer drugs, and vitamins in the design of drug–vitamin nanoparticle release systems for cancer cotherapy

R Santana, R Zuluaga, P Gañán… - Molecular …, 2020 - ACS Publications
Nanosystems are gaining momentum in pharmaceutical sciences because of the wide
variety of possibilities for designing these systems to have specific functions. Specifically …

PTML model of ChEMBL compounds assays for vitamin derivatives

R Santana, R Zuluaga, P Ganan… - ACS Combinatorial …, 2020 - ACS Publications
Determining the biological activity of vitamin derivatives is needed given that organic
synthesis of analogs of vitamins is an active field of interest for medicinal chemistry …

Machine learning guided prediction of warfarin blood levels for personalized medicine based on clinical longitudinal data from cardiac surgery patients: a prospective …

L Xue, S He, RK Singla, Q Qin, Y Ding… - … Journal of Surgery, 2024 - journals.lww.com
Background: Warfarin is a common oral anticoagulant, and its effects vary widely among
individuals. Numerous dose-prediction algorithms have been reported based on cross …

Machine learning as a proposal for a better application of food nanotechnology regulation in the European Union

R Santana, E Onieva, R Zuluaga… - Current Topics in …, 2020 - ingentaconnect.com
Aims: Given the current gaps of scientific knowledge and the need of efficient application of
food law, this paper makes an analysis of principles of European food law for the …

Implementación y optimización de algoritmos para aprendizaje automático con teoría de perturbaciones

DB Ortega Tenezaca - 2023 - ruc.udc.es
En la actualidad se ha acumulado una ingente cantidad de datos relacionados con
sistemas complejos de muy variada indole: biomoleculares, economicos, sociales, etc …

[PDF][PDF] 5) Modelling Vitamin Derivatives

I Newton - Ricardo Santana Cabello, 2021 - repository.upb.edu.co
Determining the biological activity of vitamins derivatives is needed given that organic
synthesis of analogs of vitamins is an active field of interest for Medicinal Chemistry …

[PDF][PDF] Predictive Modeling with Machine Learning and Perturbation Theory

B Ortega-Tenezaca, V Quevedo-Tumailli - 2021 - sciforum.net
PTML is a combination of Machine Learning (ML) and Perturbation Theory (PT) that allows
to create prediction models in many areas of knowledge mainly in Medicinal Chemistry to …