Background This is an update of the original Cochrane review first published in Issue 1,
2003, and previously updated in 2009, 2012 and 2014. Chronic pain, defined as pain that …

Opioid therapy is the cornerstone of treatment for acute procedural and postoperative pain
and is regularly prescribed for severe and debilitating chronic pain conditions. Although …

Background Reports of the overall chronic pain prevalence and its associated demographic
characteristics among adolescents vary greatly across existing studies. Using internationally …

Chronic pain is a prevalent and persistent problem in middle childhood and adolescence.
The biopsychosocial model of pain, which accounts for the complex interplay of the …

We know little about the safety or efficacy of pharmacological medicines for children and
adolescents with chronic pain, despite their common use. Our aim was to conduct an …

Persistent postsurgical pain (PPSP) or chronic postsurgical pain (CPSP) is a recognized
complication following surgical interventions in adults. There is no universally agreed …

Chronic noncancer pain in children and adolescents can be impairing and results in
substantial health care costs. Intensive interdisciplinary pain treatment (IIPT), an inpatient or …

Background: Chronic pain affects 1–3 million Canadian children and adolescents and their
families. The primary objective of the Partnering For Pain project was to collaboratively …

Complex regional pain syndrome (CRPS) is a relatively new diagnostic entity in pediatrics.
There is debate as to what constitutes the most effective treatment for pediatric CRPS. This …

Objective Parental factors are central in the development and maintenance of chronic pain
in youths. Only a handful of studies have investigated the impact of psychological treatments …