Drosophila olfactory memory: single genes to complex neural circuits

AC Keene, S Waddell - Nature Reviews Neuroscience, 2007 - nature.com
A central goal of neuroscience is to understand how neural circuits encode memory and
guide behaviour. Studying simple, genetically tractable organisms, such as Drosophila …

Deconstructing memory in Drosophila

C Margulies, T Tully, J Dubnau - Current biology, 2005 - cell.com
Unlike most organ systems, which have evolved to maintain homeostasis, the brain has
been selected to sense and adapt to environmental stimuli by constantly altering interactions …

Genetic dissection of consolidated memory in Drosophila

T Tully, T Preat, SC Boynton, M Del Vecchio - Cell, 1994 - cell.com
Behavioral and pharmacological experiments in many animal species have suggested that
memory is consolidated from an initial, disruptable form into a longlasting, stable form within …

Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila

JCP Yin, JS Wallach, M Del Vecchio, EL Wilder… - Cell, 1994 - Elsevier
Consolidated memory after olfactory learning in Drosophila consists of two components, a
cycloheximide-sensitive, long-term memory (LTM) and a cycloheximide-insensitive …

CREB as a memory modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila

JCP Yin, M Del Vecchio, H Zhou, T Tully - Cell, 1995 - cell.com
Genetic studies of memory formation in Drosophila have revealed that the formation of a
protein synthesis-dependent long-term memory (LTM) requires multiple training sessions …

The staufen/pumilio pathway is involved in Drosophila long-term memory

J Dubnau, AS Chiang, L Grady, J Barditch… - Current Biology, 2003 - cell.com
Background: Memory formation after olfactory learning in Drosophila displays behavioral
and molecular properties similar to those of other species. Particularly, long-term memory …

[HTML][HTML] Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth

W Lu, V Yamamoto, B Ortega, D Baltimore - Cell, 2004 - cell.com
The Ryk receptor belongs to the atypical receptor tyrosine kinase family. It is a new member
of the family of Wnt receptor proteins. However, the molecular mechanisms by which the Ryk …

The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster

E Ryder, F Blows, M Ashburner, R Bautista-Llacer… - Genetics, 2004 - academic.oup.com
We describe a collection of P-element insertions that have considerable utility for generating
custom chromosomal aberrations in Drosophila melanogaster. We have mobilized a pair of …

Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation

J Chen, CS Park, SJ Tang - Journal of Biological Chemistry, 2006 - ASBMB
Wnts are important for various developmental and oncogenic processes. Here we show that
Wnt signaling functions at synapses in hippocampal neurons. Tetanic stimulations induce N …

[HTML][HTML] Canonical and noncanonical Wnt signaling: multilayered mediators, signaling mechanisms and major signaling crosstalk

K Qin, M Yu, J Fan, H Wang, P Zhao, G Zhao, W Zeng… - Genes & …, 2024 - Elsevier
Wnt signaling plays a major role in regulating cell proliferation and differentiation. The Wnt
ligands are a family of 19 secreted glycoproteins that mediate their signaling effects via …