Biosynthesis, extraction, detection and pharmacological attributes of vinblastine and vincristine, two important chemotherapeutic alkaloids of Catharanthus roseus (L.) …

A Paul, K Acharya, N Chakraborty - South African Journal of Botany, 2023 - Elsevier
The demand for natural product is growing their interest in our daily life. It makes
Catharanthus roseus (L.) G. Don a crucial member of family Apocynaceae due to having its …

Present status of Catharanthus roseus monoterpenoid indole alkaloids engineering in homo- and hetero-logous systems

A Sharma, D Amin, A Sankaranarayanan, R Arora… - Biotechnology …, 2020 - Springer
Catharanthus roseus synthesizes one of the most structurally, chemically and biologically
active phytomolecules monoterpenoids indole alkaloids (MIAs) with having a wide range of …

[图书][B] Millets and millet technology

A Kumar, MK Tripathi, D Joshi, V Kumar - 2021 - Springer
Globalization and industrialization of agriculture although benefitted with adequate food
supplies, its negative side effects have also been realized particularly with respect to loss of …

Function of AP2/ERF Transcription Factors Involved in the Regulation of Specialized Metabolism in Ophiorrhiza pumila Revealed by Transcriptomics and …

N Udomsom, A Rai, H Suzuki, J Okuyama… - Frontiers in plant …, 2016 - frontiersin.org
The hairy roots (HR) of Ophiorrhiza pumila produce camptothecin (CPT), a monoterpenoid
indole alkaloid used as a precursor in the synthesis of chemotherapeutic drugs. O. pumila …

[图书][B] Plant biochemistry

C Bowsher, M Steer, A Tobin - 2008 - api.taylorfrancis.com
Plant Biochemistry presents each topic from the cellular level to the ecological and
environmental levels, placing it in the context of the whole plant. Biochemical pathways are …

Overexpression of tryptophan decarboxylase and strictosidine synthase enhanced terpenoid indole alkaloid pathway activity and antineoplastic vinblastine …

A Sharma, P Verma, A Mathur, AK Mathur - Protoplasma, 2018 - Springer
Terpenoid indole alkaloid (TIA) biosynthetic pathway of Catharanthus roseus possesses the
major attention in current metabolic engineering efforts being the sole source of highly …

Genetic engineering approach using early Vinca alkaloid biosynthesis genes led to increased tryptamine and terpenoid indole alkaloids biosynthesis in differentiating cultures of …

A Sharma, P Verma, A Mathur, AK Mathur - Protoplasma, 2018 - Springer
Catharanthus roseus today occupies the central position in ongoing metabolic engineering
efforts in medicinal plants. The entire multi-step biogenetic pathway of its very expensive …

Enhancement of Vindoline and Catharanthine Accumulation, Antioxidant Enzymes Activities, and Gene Expression Levels in Catharanthus roseus Leaves by …

W Tang, X Liu, Y He, F Yang - Marine Drugs, 2022 - mdpi.com
Catharanthus roseus (L.) G. Don is a plant belonging to the genus Catharanthus of the
Apocynaceae family. It contains more than one hundred alkaloids, of which some exhibit …

[图书][B] Catharanthus roseus

M Naeem, T Aftab, MMA Khan - 2017 - Springer
Catharanthus roseus M. Naeem· Tariq Aftab M. Masroor A. Khan Editors Catharanthus roseus
Current Research and Future Prospects Page 2 Catharanthus roseus Page 3 M. Naeem• Tariq …

Tropinone reductase: A comprehensive review on its role as the key enzyme in tropane alkaloids biosynthesis

X Hu, W Liu, Y Yan, H Deng, Y Cai - International Journal of Biological …, 2023 - Elsevier
TAs, including hyoscyamine and scopolamine, were used to treat neuromuscular disorders
ranging from nerve agent poisoning to Parkinson's disease. Tropinone reductase I (TR-I; EC …