Enolase is a glycolytic enzyme, which catalyzes the inter-conversion of 2-phosphoglycerate
to phosphoenolpyruvate. Altered expression of this enzyme is frequently observed in cancer …

Abstract Enolase 1 (ENO1) is a moonlighting protein, function as a glycolysis enzyme, a
plasminogen receptor and a DNA binding protein. ENO1 play an important role in the …

Breast cancer is one of the most common cancers among women in the United States.
Although there are effective drugs for treating advanced stages of breast cancers, women …

Breast cancer is a complex and heterogeneous disease: Several molecular alterations
cause cell proliferation and the acquisition of an invasive phenotype. Extracellular matrix …

2-DE in combination with MS is a widely used proteomic technology platform in comparative
protein profiling studies for the identification of biomarkers for specific conditions (eg …

Multiple, complex molecular events characterize cancer development and progression.
Deciphering the molecular networks that distinguish organ-confined disease from metastatic …

Mitogen-activated protein kinase (MAPK) cascades are evolutionarily conserved signaling
pathways that play essential roles in transducing extracellular environmental signals into …

Hepatitis C virus (HCV)–mediated chronic liver disease is a serious health problem around
the world and often causes fibrosis/cirrhosis and hepatocellular carcinoma. The mechanism …

microRNAs (miRNAs) are a growing class of small non-coding RNAs that exhibit
widespread dysregulation in prostate cancer. We profiled miRNA expression in syngeneic …

Prostate cancer remains the second leading cause of cancer deaths among American men.
Earlier diagnosis increases survival rate in patients. However, treatments for advanced …