[HTML][HTML] Gene methylation in gastric cancer

Y Qu, S Dang, P Hou - Clinica chimica acta, 2013 - Elsevier
Gastric cancer is one of the most common malignancies and remains the second leading
cause of cancer-related death worldwide. Over 70% of new cases and deaths occur in …

[HTML][HTML] CMTM family proteins 1–8: roles in cancer biological processes and potential clinical value

J Wu, L Li, S Wu, B Xu - Cancer Biology & Medicine, 2020 - ncbi.nlm.nih.gov
The CKLF-like MARVEL transmembrane domain containing (CMTM) family of genes
comprises CKLF and CMTM1–8 (previously called chemokine-like factor superfamily 1–8 …

Methylation of multiple genes as a candidate biomarker in non-small cell lung cancer

Y Zhang, R Wang, H Song, G Huang, J Yi, Y Zheng… - Cancer letters, 2011 - Elsevier
Aberrant DNA methylation is a common phenomenon in human cancer. The aims of this
study were to investigate the methylation profiles of non-small cell lung cancer (NSCLC) in …

The ubiquitin peptidase UCHL1 induces G0/G1 cell cycle arrest and apoptosis through stabilizing p53 and is frequently silenced in breast cancer

T Xiang, L Li, X Yin, C Yuan, C Tan, X Su, L Xiong… - PloS one, 2012 - journals.plos.org
Background Breast cancer (BrCa) is a complex disease driven by aberrant gene alterations
and environmental factors. Recent studies reveal that abnormal epigenetic gene regulation …

KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas

Y Cheng, H Geng, SH Cheng, P Liang, Y Bai, J Li… - Cancer research, 2010 - AACR
Zinc finger transcription factors are involved broadly in development and tumorigenesis.
Here, we report that the little studied zinc finger transcription factor ZNF382 functions as a …

The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas

L Li, J Ying, H Li, Y Zhang, X Shu, Y Fan, J Tan, Y Cao… - Oncogene, 2012 - nature.com
Genetic alterations of 16q21-q22, the locus of a 6-cadherin cluster, are frequently involved in
multiple tumors, suggesting the presence of critical tumor suppressor genes (TSGs). Using 1 …

CMTM4 regulates angiogenesis by promoting cell surface recycling of VE-cadherin to endothelial adherens junctions

I Chrifi, L Louzao-Martinez, MM Brandt, CGM Van Dijk… - Angiogenesis, 2019 - Springer
Vascular endothelial (VE) cadherin is a key component of endothelial adherens junctions
(AJs) and plays an important role in maintaining vascular integrity. Endocytosis of VE …

CMTM7 inhibits breast cancer progression by regulating Wnt/β-catenin signaling

ZH Chen, Y Tian, GL Zhou, HR Yue, XJ Zhou… - Breast Cancer …, 2023 - Springer
Background Breast cancer is the major cause of death in females globally. Chemokine-like
factor like MARVEL transmembrane domain containing 7 (CMTM7) is reported as a tumor …

A novel 3p22. 3 gene CMTM7 represses oncogenic EGFR signaling and inhibits cancer cell growth

H Li, J Li, Y Su, Y Fan, X Guo, L Li, X Su, R Rong… - Oncogene, 2014 - nature.com
Abstract Deletion of 3p12-22 is frequent in multiple cancer types, indicating the presence of
critical tumor-suppressor genes (TSGs) at this region. We studied a novel candidate TSG …

CMTM3 decreases EGFR expression and EGF-mediated tumorigenicity by promoting Rab5 activity in gastric cancer

W Yuan, B Liu, X Wang, T Li, H Xue, X Mo, S Yang… - Cancer Letters, 2017 - Elsevier
Abstract CMTM3 (CKLF-like MARVEL transmembrane domain containing 3), a tumor
suppressor gene, is involved in multiple types of malignancies. CMTM3 knockdown …