N-acetylcysteine (NAC) is a medicine widely used to treat paracetamol overdose and as a
mucolytic compound. It has a well-established safety profile, and its toxicity is uncommon …

A growing body of evidence has emerged demonstrating a pathological link between
oxidative stress and schizophrenia. This evidence identifies oxidative stress as a …

Abstract N-acetyl-L-cysteine (NAC) is a compound of increasing interest in the treatment of
psychiatric disorders. Primarily through its antioxidant, anti-inflammatory, and glutamate …

The prevalence of autism spectrum disorder (ASD)—a type of neurodevelopmental disorder—
is increasing and is around 2% in North America, Asia, and Europe. Besides the known …

Converging evidence implicates redox dysregulation as a pathological mechanism driving
the emergence of psychosis. Increased oxidative damage and decreased capacity of …

Treatment of schizophrenia (SCZ) historically relies on the use of antipsychotic drugs to treat
psychosis, with all of the currently available antipsychotics acting through the antagonism of …

Background Currently approved medications for schizophrenia are relatively ineffective for
negative symptoms and cognitive impairment. N-Acetyl Cysteine (NAC) is a neuroprotective …

Redox biology and immune signaling play major roles in the body, including in brain
function. A rapidly growing literature also suggests that redox and immune abnormalities are …

Schizophrenia is associated with alterations of sensory integration, cognitive processing and
both sleep architecture and sleep oscillations in mouse models and human subjects …

Schizophrenia (SCZ) is a severe neurodevelopmental disorder affecting 1% of populations
worldwide with a grave disability and socioeconomic burden. Current antipsychotic …