Nitric oxide is a versatile mediator formed by enzymes called nitric oxide synthases. It has
numerous homeostatic functions and important roles in inflammation. Within the inflamed …

Background Previous studies have shown beneficial effects of mesenchymal stem cell
(MSC) transplantation in central nervous system (CNS) injuries, including traumatic brain …

Nerve injury–induced neuropathic pain is difficult to treat. In this study, we used exosomes
derived from human umbilical cord mesenchymal stem cell (UCMSC) as a cell-free therapy …

Traumatic brain injury (TBI), a leading cause of morbidity and mortality throughout the world,
will probably become the third cause of death in the world by the year 2020. Lack of effective …

Traumatic brain injury (TBI) is soon predicted to become the third leading cause of death
and disability worldwide. After the primary injury, a complex set of secondary injuries …

Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), are driven by
neuroinflammation triggered by activated microglial cells; hence, the phenotypic regulation …

Background Magnesium sulfate has been used as an anticonvulsant in severe preeclamptic
or eclamptic women prior to surgical trauma, but its effects on neuroinflammation is not well …

More than 6.5 million patients are burdened by the physical, cognitive, and psychosocial
deficits associated with traumatic brain injury (TBI) in the US Despite extensive efforts to …

Increasing global birth rate, coupled with the aging population surviving into their eighth
decade has lead to increased incidence diseases, hitherto designated as rare. Brain related …

Mesenchymal stems or stromal cells (MSCs) are rare multipotent cells with potent
regenerative and immunomodulatory properties. Microglial cells (MGs) are specialized …