Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies
RD Klein, SJ Hultgren - Nature Reviews Microbiology, 2020 - nature.com
Urinary tract infections (UTIs) are common, recurrent infections that can be mild to life-
threatening. The continued emergence of antibiotic resistance, together with our increasing …
threatening. The continued emergence of antibiotic resistance, together with our increasing …
UroPathogenic Escherichia coli (UPEC) Infections: Virulence Factors, Bladder Responses, Antibiotic, and Non-antibiotic Antimicrobial Strategies
ME Terlizzi, G Gribaudo, ME Maffei - Frontiers in microbiology, 2017 - frontiersin.org
Urinary tract infections (UTIs) are one of the most common pathological conditions in both
community and hospital settings. It has been estimated that about 150 million people …
community and hospital settings. It has been estimated that about 150 million people …
Dendritic cells and macrophages in the pathogenesis of psoriasis
M Kamata, Y Tada - Frontiers in immunology, 2022 - frontiersin.org
Psoriasis is a chronic inflammatory skin disease characterized by scaly indurated erythema.
This disease impairs patients' quality of life enormously. Pathological findings demonstrate …
This disease impairs patients' quality of life enormously. Pathological findings demonstrate …
Neutrophil migration in infection and wound repair: going forward in reverse
S De Oliveira, EE Rosowski… - Nature Reviews …, 2016 - nature.com
Neutrophil migration and its role during inflammation has been the focus of increased
interest in the past decade. Advances in live imaging and the use of new model systems …
interest in the past decade. Advances in live imaging and the use of new model systems …
Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair
W Yang, Y Tao, Y Wu, X Zhao, W Ye, D Zhao… - Nature …, 2019 - nature.com
Phagocytes, including neutrophils and macrophages, have been suggested to function in a
cooperative way in the initial phase of inflammatory responses, but their interaction and …
cooperative way in the initial phase of inflammatory responses, but their interaction and …
New insights into the multidimensional concept of macrophage ontogeny, activation and function
Macrophages have protective roles in immunity to pathogens, tissue development,
homeostasis and repair following damage. Maladaptive immunity and inflammation provoke …
homeostasis and repair following damage. Maladaptive immunity and inflammation provoke …
Neutrophils at work
WM Nauseef, N Borregaard - Nature immunology, 2014 - nature.com
In this Review we discuss data demonstrating recently recognized aspects of neutrophil
homeostasis in the steady state, granulopoiesis in'emergency'conditions and interactions of …
homeostasis in the steady state, granulopoiesis in'emergency'conditions and interactions of …
Immune defenses in the urinary tract
HW Kuhn, TN Hreha, DA Hunstad - Trends in Immunology, 2023 - cell.com
Recent advances in preclinical modeling of urinary tract infections (UTIs) have enabled the
identification of key facets of the host response that influence pathogen clearance and tissue …
identification of key facets of the host response that influence pathogen clearance and tissue …
Tissue-resident B cells orchestrate macrophage polarisation and function
B cells play a central role in humoral immunity but also have antibody-independent
functions. Studies to date have focused on B cells in blood and secondary lymphoid organs …
functions. Studies to date have focused on B cells in blood and secondary lymphoid organs …
The nature of immune responses to urinary tract infections
SN Abraham, Y Miao - Nature Reviews Immunology, 2015 - nature.com
The urinary tract is constantly exposed to microorganisms that inhabit the gastrointestinal
tract, but generally the urinary tract resists infection by gut microorganisms. This resistance …
tract, but generally the urinary tract resists infection by gut microorganisms. This resistance …