How to classify pituitary neuroendocrine tumors (PitNET) s in 2020

J Trouillas, ML Jaffrain-Rea, A Vasiljevic, G Raverot… - Cancers, 2020 - mdpi.com
Adenohypophyseal tumors, which were recently renamed pituitary neuroendocrine tumors
(PitNET), are mostly benign, but may present various behaviors: invasive,“aggressive” and …

POU domain factors in the neuroendocrine system: lessons from developmental biology provide insights into human disease

B Andersen, MG Rosenfeld - Endocrine reviews, 2001 - academic.oup.com
POU domain factors are transcriptional regulators characterized by a highly conserved DNA-
binding domain referred to as the POU domain. The structure of the POU domain has been …

Immortalized cell lines and methods of making the same

JR Musick, JC Gill IV, BP Burnett… - US Patent 6,458,593, 2002 - Google Patents
The desirability of generating immortalized cell lines for use as in Vitro models of various
tissues has long been recognized. For example, researchers have endeavored for Some …

Paracrine/autocrine control of female reproduction

FM Reis, L Cobellis, S Luisi, L Driul… - Gynecological …, 2000 - Taylor & Francis
Neuropeptides, growth factors and cytokines are expressed in reproductive organs and
tissues, where they interact with afferent endocrine messages to modulate cell proliferation …

Correlation of Pit-1 gene expression and Pit-1 content with proliferation and differentiation in human myeloid leukemic cells

JA Costoya, M Garcıa-Barros, R Gallego… - Experimental cell …, 1998 - Elsevier
The transcription factor pituitary-1 (Pit-1) is a homeodomain-containing protein that is
expressed mainly in the pituitary, where it drives the expression of growth hormone …

Pit-1 positive alpha-subunit positive nonfunctioning human pituitary adenomas: a dedifferentiated GH cell lineage?

RY Osamura, S Tahara, K Komatsubara, Y Itoh… - Pituitary, 1999 - europepmc.org
Pit-1 is a transcription factor which has been reported to regulate differentiation toward GH,
PRL and TSH in the anterior pituitary glands. In the human pituitary adenomas, Pit-1 is …

GH-, PRL-, POMC-, β-TSH-, β-LH-, β-FSH-mRNA in gonadotroph adenomas of the pituitary by In Situ hybridization in comparison with immunostaining and clinical …

A Münscher, M Schmid, W Saeger, S Schreiber… - Endocrine …, 2001 - Springer
In situ hybridization (ISH) enables the visualization of specific mRNA for pituitary hormones.
Our collection consists of 40 surgically removed pituitary adenomas that were classified as …

Immunonegative null cell ″adenomas and Gnadotropin (G) Subunit (Su) immunopositive adenomas share frequent expression of multiple transcription factors

Y Ishii, M Suzuki, S Takekoshi, N Egashira… - Endocrine …, 2006 - Springer
The differentiation of pituitary cells and human pituitary adenomas follow three cell lineages:
H-PRTSH, ACTH, and FSHH, which are regulated by a combination of various transcription …

[HTML][HTML] Immortalized cell lines and methods of making the same

JR Musick - uspto.report
The present invention relates to methods of immortalizing various primary cell cultures,
including pituitary cells, neurons, beta islet cells, glial cells, corneal epithelial cells and …

Immortalized cell lines and methods of making the same

J Musick, J Gill, B Burnett, T Hedlund - US Patent App. 10/219,058, 2003 - Google Patents
The present invention relates to methods of immortalizing various primary cell cultures,
including pituitary cells, neu rons, beta islet cells, glial cells, corneal epithelial cells and …