Piperazine is one of the most sought heterocyclics for the development of new drug
candidates. This ring can be traced in a number of well established, commercially available …

Pyrazoles are known as versatile scaffolds in organic synthesis and medicinal chemistry,
often used as starting materials for the preparation of more complex heterocyclic systems …

Cyrene as a bio-alternative solvent: a highly efficient, waste minimizing protocol for the
synthesis of ureas from isocyanates and secondary amines in the bio-available solvent …

Malaria is a tropical disease, prevalent in Southeast Asia and Africa, resulting in over half a
million deaths annually; efforts to develop new antimalarial agents are therefore particularly …

Malaria remains a major vector borne disease claiming millions of lives worldwide due to
infections caused by Plasmodium sp. Discovery and development of antimalarial drugs have …

A novel series of pyrazolyl chalcones containing quinoline scaffold, 5 av has been
synthesized by Claisen Schimdt condensation of aromatic acetophenone with 1-(4 …

A green and efficient visible-light promoted oxidative desulphurisation protocol has been
proposed for the construction of unsymmetrical ureas under mild conditions with broad …

In this work, a series of quinoline derivatives were designed and synthesized as antitumor
agents. Most quinolines showed potent anti-proliferative activity against human prostatic …

Abstract Triazole tethered 7-chloroquinoline-pyrimidine-5-carboxylate hybrids were
synthesized and evaluated for antiplasmodial activity against chloroquine sensitive (CQ S) …

Parasitic diseases have serious health, social, and economic impacts, especially in the
tropical regions of the world. Diseases caused by protozoan parasites are responsible for …