Abstract N6-methyladenosine (m6A) has emerged as an abundant modification throughout
the transcriptome with widespread functions in protein-coding and noncoding RNAs. It …

Ongoing research has revealed that the existence of cancer stem cells (CSCs) is one of the
biggest obstacles in the current cancer therapy. CSCs make an influential function in tumor …

Despite the exciting breakthroughs in medical technology, cancer still accounts for one of
the principle triggers of death and conventional therapeutic modalities often fail to attain an …

Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …

Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

Sex-determining region Y-box2 (SOX2), a master regulator of embryonic and induced
pluripotent stem cells, drives cancer stem cells (CSCs) properties, fuels tumor initiation, and …

Cancer stem cells (CSCs) are an important cause of tumor recurrence and drug resistance.
As a new type of cell death that relies on iron ions and is strictly regulated by intracellular …

Cancer is a complicated disease attributed to multifactorial changes, which causes
difficulties with treatment strategies. Various factors have been regarded as the main …

Background Patients with lymph node (LN) metastatic bladder cancer (BCa) present with
extremely poor prognosis. BCa‐derived exosomes function as crucial bioactive cargo …

Simple Summary Hypoxia is defined as the inadequate supply of oxygen in tissues. Regions
of acute and chronic hypoxia are a universal feature of the tumor microenvironment and a …