Process analytical technologies and self-optimization algorithms in automated pharmaceutical continuous manufacturing
P Liu, H Jin, Y Chen, D Wang, H Yan, M Wu… - Chinese Chemical …, 2024 - Elsevier
The pharmaceutical industry is now paying increased attention to continuous manufacturing.
While the revolution to continuous and automated manufacturing is deepening in most of the …
While the revolution to continuous and automated manufacturing is deepening in most of the …
Particle design via spherical agglomeration: A critical review of controlling parameters, rate processes and modelling
Particle design via spherical agglomeration is a size enlargement technique used in various
bulk and fine chemical industries, with recent interest extending into pharmaceuticals, in …
bulk and fine chemical industries, with recent interest extending into pharmaceuticals, in …
Continuous crystallization processes in pharmaceutical manufacturing: A review
J Orehek, D Teslic, B Likozar - Organic Process Research & …, 2020 - ACS Publications
This scientific paper presents an overview of continuous solution crystallization in the
pharmaceutical industry. Since the specific knowledge spectrum of precipitation is very …
pharmaceutical industry. Since the specific knowledge spectrum of precipitation is very …
Integrated continuous pharmaceutical technologies—a review
Innovation in the pharmaceutical industry has been limited for a long time to the research
and development of new active compounds; meanwhile, the structure of the production …
and development of new active compounds; meanwhile, the structure of the production …
Progress to date in the design and operation of continuous crystallization processes for pharmaceutical applications
Continuous crystallization has gained interest in the pharmaceutical sector as part of the
drive toward the transition from exclusive batch manufacturing to integrated continuous …
drive toward the transition from exclusive batch manufacturing to integrated continuous …
Recent progress in continuous crystallization of pharmaceutical products: precise preparation and control
Crystallization, as a solid–liquid separation process, is employed to purify and isolate a
great diversity of crystalline pharmaceutical products. In recent years, continuous …
great diversity of crystalline pharmaceutical products. In recent years, continuous …
Nucleation and crystal growth in continuous crystallization
J McGinty, N Yazdanpanah, C Price, JH ter Horst… - 2020 - books.rsc.org
Continuous crystallization has been a common process in the fine chemicals and
petrochemical industries for decades. the advantage of continuous crystallization led other …
petrochemical industries for decades. the advantage of continuous crystallization led other …
[HTML][HTML] End-to-end continuous manufacturing of conventional compressed tablets: From flow synthesis to tableting through integrated crystallization and filtration
An end-to-end continuous pharmaceutical manufacturing process was developed for the
production of conventional direct compressed tablets on a proof-of-concept level for the first …
production of conventional direct compressed tablets on a proof-of-concept level for the first …
Current trends in API co-processing: spherical crystallization and co-precipitation techniques
Abstract Active Pharmaceutical Ingredients (APIs) do not always exhibit processable
physical properties, which makes their processing in an industrial setup very demanding …
physical properties, which makes their processing in an industrial setup very demanding …
Design of the spherical agglomerate size in crystallization by developing a two‐step bridging mechanism and the model
Spherical agglomeration technology can produce high‐performance spherical particles in a
single crystallization unit, although it is still challenging to control the particle size and …
single crystallization unit, although it is still challenging to control the particle size and …