Life expectancy of HIV-positive adults: a review

MT May, SM Ingle - Sexual health, 2011 - CSIRO Publishing
We review studies estimating life expectancy (LE), the average number of additional years a
person can expect to live, for HIV-positive adults and show variation by sociodemographic …

Abacavir: a review of its clinical potential in patients with HIV infection

PS Hervey, CM Perry - Drugs, 2000 - Springer
Abacavir is a carbocyclic 2′-deoxyguanosine nucleoside analogue. It is metabolised
intracellularly to a 2′-deoxyguanosine nucleoside analogue which competitively inhibits …

Impact of late diagnosis and treatment on life expectancy in people with HIV-1: UK Collaborative HIV Cohort (UK CHIC) Study

M May, M Gompels, V Delpech, K Porter, F Post… - Bmj, 2011 - bmj.com
Objectives To estimate life expectancy for people with HIV undergoing treatment compared
with life expectancy in the general population and to assess the impact on life expectancy of …

Episodic sexual transmission of HIV revealed by molecular phylodynamics

F Lewis, GJ Hughes, A Rambaut, A Pozniak… - PLoS …, 2008 - journals.plos.org
Background The structure of sexual contact networks plays a key role in the epidemiology of
sexually transmitted infections, and their reconstruction from interview data has provided …

Effect of Medication Adherence on Survival of HIV-Infected Adults Who Start Highly Active Antiretroviral Therapy When the CD4+ Cell Count Is 0.200 to 0.350 × 109 …

E Wood, RS Hogg, B Yip, PR Harrigan… - Annals of internal …, 2003 - acpjournals.org
Background: The safety of delaying highly active antiretroviral therapy (HAART) in HIV-
infected patients is uncertain when the CD4+ cell count declines below 0.350× 109 cells/L …

Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection

GK Robbins, V De Gruttola, RW Shafer… - … England Journal of …, 2003 - Mass Medical Soc
Background The optimal sequencing of antiretroviral regimens for the treatment of infection
with human immunodeficiency virus type 1 (HIV-1) is unknown. We compared several …

Transmission network parameters estimated from HIV sequences for a nationwide epidemic

AJ Leigh Brown, SJ Lycett, L Weinert… - Journal of Infectious …, 2011 - academic.oup.com
Background. Many studies of sexual behavior have shown that individuals vary greatly in
their number of sexual partners over time, but it has proved difficult to obtain parameter …

Predictors of virologic failure and resistance in HIV-infected patients treated with nevirapine-or efavirenz-based antiretroviral therapy

JJ Parienti, V Massari, D Descamps… - Clinical Infectious …, 2004 - academic.oup.com
Resistance to nonnucleoside reverse transcriptase inhibitors (NNRTIs) increases with the
wider use of this class of antiretroviral therapy. The association between adherence and …

Patients' perceptions of highly active antiretroviral therapy in relation to treatment uptake and adherence: the utility of the necessity-concerns framework

R Horne, V Cooper, G Gellaitry, HL Date… - JAIDS Journal of …, 2007 - journals.lww.com
Objective: To test the utility of the necessity-concerns framework in predicting highly active
antiretroviral therapy (HAART) uptake and adherence. Methods: This was a prospective …

Abacavir-lamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial

S Staszewski, P Keiser, J Montaner, F Raffi, J Gathe… - Jama, 2001 - jamanetwork.com
ContextAbacavir, a nucleoside analogue, has demonstrated suppression of human
immunodeficiency virus (HIV) replication alone and in combination therapy. However, the …