[HTML][HTML] Deep brain stimulation for depression

M Figee, P Riva-Posse, KS Choi, L Bederson… - …, 2022 - Elsevier
Deep brain stimulation has been extensively studied as a therapeutic option for treatment-
resistant depression (TRD). DBS across different targets is associated with on average 60 …

Biomarkers for closed-loop deep brain stimulation in Parkinson disease and beyond

W Bouthour, P Mégevand, J Donoghue… - Nature Reviews …, 2019 - nature.com
Subthalamic deep brain stimulation (DBS) for Parkinson disease (PD) currently requires
laborious open-loop programming, which can mitigate the benefits of this treatment …

Cingulate dynamics track depression recovery with deep brain stimulation

S Alagapan, KS Choi, S Heisig, P Riva-Posse… - Nature, 2023 - nature.com
Deep brain stimulation (DBS) of the subcallosal cingulate (SCC) can provide long-term
symptom relief for treatment-resistant depression (TRD). However, achieving stable recovery …

Proceedings of the eighth annual deep brain stimulation think tank: advances in optogenetics, ethical issues affecting DBS research, neuromodulatory approaches for …

V Vedam-Mai, K Deisseroth, J Giordano… - Frontiers in Human …, 2021 - frontiersin.org
We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to
address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters …

Deep brain stimulation for refractory major depressive disorder: a comprehensive review

KA Johnson, MS Okun, KW Scangos, HS Mayberg… - Molecular …, 2024 - nature.com
Deep brain stimulation (DBS) has emerged as a promising treatment for select patients with
refractory major depressive disorder (MDD). The clinical effectiveness of DBS for MDD has …

Intraoperative neural signals predict rapid antidepressant effects of deep brain stimulation

MSE Sendi, AC Waters, V Tiruvadi… - Translational …, 2021 - nature.com
Deep brain stimulation (DBS) of the subcallosal cingulate (SCC) is a promising intervention
for treatment-resistant depression (TRD). Despite the failure of a clinical trial, multiple case …

Field potential 1/f activity in the subcallosal cingulate region as a candidate signal for monitoring deep brain stimulation for treatment-resistant depression

A Veerakumar, V Tiruvadi, B Howell… - Journal of …, 2019 - journals.physiology.org
Subcallosal cingulate cortex deep brain stimulation (SCC-DBS) is an experimental therapy
for treatment-resistant depression (TRD). Refinement and optimization of SCC-DBS will …

[HTML][HTML] Local neuroanatomical and tract-based proxies of optimal subcallosal cingulate deep brain stimulation

GJB Elias, J Germann, A Boutet, ME Beyn, P Giacobbe… - Brain stimulation, 2023 - Elsevier
Background Deep brain stimulation of the subcallosal cingulate area (SCC-DBS) is a
promising neuromodulatory therapy for treatment-resistant depression (TRD). Biomarkers of …

Whole brain network effects of subcallosal cingulate deep brain stimulation for treatment-resistant depression

J Cha, KS Choi, JK Rajendra, CL McGrath… - Molecular …, 2024 - nature.com
Ongoing experimental studies of subcallosal cingulate deep brain stimulation (SCC DBS) for
treatment-resistant depression (TRD) show a differential timeline of behavioral effects with …

Quantifying the axonal pathways directly stimulated in therapeutic subcallosal cingulate deep brain stimulation

B Howell, KS Choi, K Gunalan, J Rajendra… - Human brain …, 2019 - Wiley Online Library
Deep brain stimulation (DBS) of the subcallosal cingulate (SCC) is an emerging
experimental therapy for treatment‐resistant depression. New developments in SCC DBS …