Neuronal apoptosis is important in the developmental sculpting of a normal nervous system
and also in the loss of neurons caused by neurodegenerative disease, ischemia or trauma …

During development of the primary olfactory system, axon targeting is inaccurate and axons
inappropriately project within the target layer or overproject into the deeper layers of the …

GnRH neurons are essential for the onset and maintenance of reproduction. Mutations in
both fibroblast growth factor receptor (Fgfr1) and Fgf8 have been shown to cause Kallmann …

Olfactory receptor neurons (ORNs) were infected upon intranasal inoculation with the
R404BP strain of neurovirulent influenza A virus. Virus-infected neurons and a small fraction …

The ventromedial hypothalamic nucleus (VMN) is known to mediate autonomic responses in
feeding and reproductive behaviors. To date, the most definitive molecular marker for the …

Activating transcription factor 5 (ATF5) is a member of the ATF/cAMP response element-
binding family of transcription factors, which compose a large group of basic region leucine …

The histochemical detection of β-galactosidase enzymatic activity at pH 6.0 (β-gal-pH6) is a
widely used biomarker of cellular senescence in aging tissues. This histochemical assay …

Background Insm1 is a zinc-finger transcription factor transiently expressed throughout the
developing nervous system in late progenitors and nascent neurons. Insm1 is also highly …

The olfactory sensory neurons (OSNs) of the olfactory epithelium (OE) exhibit a remarkable
regenerative capability, which protects the population against environmental insult and …

The Ca 2+-activated monovalent cation channel Trpm5 is a key element in
chemotransduction of taste receptor cells of the tongue, but the extent to which Trpm5 …