Metabotropic glutamate receptors in auditory processing

Y Lu - Neuroscience, 2014 - Elsevier
As the major excitatory neurotransmitter used in the vertebrate brain, glutamate activates
ionotropic and metabotropic glutamate receptors (mGluRs), which mediate fast and slow …

[HTML][HTML] Inhibition in the balance: binaurally coupled inhibitory feedback in sound localization circuitry

RM Burger, I Fukui, H Ohmori… - Journal of …, 2011 - journals.physiology.org
Interaural time differences (ITDs) are the primary cue animals, including humans, use to
localize low-frequency sounds. In vertebrate auditory systems, dedicated ITD processing …

Functional recovery after ischemic stroke is associated with reduced GABAergic inhibition in the cerebral cortex: a GABA PET study

YK Kim, EJ Yang, K Cho, JY Lim… - … and neural repair, 2014 - journals.sagepub.com
Background: γ-Aminobutyric acid (GABA) plasticity plays an important role in stroke motor
recovery in a mouse model. However, little is known about changes over time in neuronal …

[HTML][HTML] Ginsenoside Rb1 regulates prefrontal cortical GABAergic transmission in MPTP-treated mice

Y Liu, X Zong, J Huang, Y Guan, Y Li, T Du… - Aging (albany …, 2019 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a common neurodegenerative disease, featured by motor
deficits and non-motor symptoms such as cognitive impairment, and malfunction of gamma …

Heterogeneous kinetics and pharmacology of synaptic inhibition in the chick auditory brainstem

SP Kuo, LA Bradley, LO Trussell - Journal of Neuroscience, 2009 - Soc Neuroscience
Identification of shared features between avian and mammalian auditory brainstem circuits
has provided much insight into the mechanisms underlying early auditory processing …

A developmental switch to GABAergic inhibition dependent on increases in Kv1-type K+ currents

MKA Howard, RM Burger, EW Rubel - Journal of Neuroscience, 2007 - Soc Neuroscience
Mature nucleus magnocellularis (NM) neurons, the avian homolog of bushy cells of the
mammalian anteroventral cochlear nucleus, maintain high [Cl−] i and depolarize in …

Experience-Dependent Plasticity in Nucleus Laminaris of the Barn Owl

CE Carr, T Wang, I Kraemer, G Capshaw… - Journal of …, 2024 - Soc Neuroscience
Interaural time differences (ITDs) are a major cue for sound localization and change with
increasing head size. Since the barn owl's head width more than doubles in the month after …

Modulation of synaptic input by GABAB receptors improves coincidence detection for computation of sound location

MJ Fischl, TD Combs, A Klug, B Grothe… - The Journal of …, 2012 - Wiley Online Library
Key points• Organisms localise low frequencies using interaural time disparities (ITDs) in
which specialized neurones in the medial superior olive (MSO) compute submillisecond …

Dynamics of binaural processing in the mammalian sound localization pathway–The role of GABAB receptors

B Grothe, U Koch - Hearing research, 2011 - Elsevier
The initial binaural processing in the superior olive represents the fastest computation
known in the entire mammalian brain. Although the binaural system has to perform under …

[HTML][HTML] Anatomy and physiology of metabotropic glutamate receptors in mammalian and avian auditory system

ZQ Tang, Y Lu - HSOA trends in anatomy and physiology, 2018 - ncbi.nlm.nih.gov
Glutamate, as the major excitatory neurotransmitter used in the vertebrate brain, activates
ionotropic and metabotropic glutamate receptors (iGluRs and mGluRs), which mediate fast …