Nanomedicines refers to nanotechnology inspired pharmaceutical products often referred to
as 'nanopharmaceuticals.'It has displayed commendable potential in enhancing therapeutic …

Acute lymphoblastic leukemia (ALL) is a heterogenous hematological malignancy
representing 25% of all cancers in children less than 15 years of age. Significant …

If the appropriate immobilization method and carrier support are not selected, partial
decreases in the activity of enzymes may occur after immobilization. Herein, to overcome …

Covalent attachment of therapeutic proteins to polyethylene glycol (PEG) is widely used for
the improvement of its pharmacokinetic and pharmacological properties, as well as the …

Bacterial L-asparaginase is the key therapeutic enzyme in cancer therapy and is also
witnessing demand as a food processing aid. In this study, L-asparaginase of newly isolated …

Acrylamide is a potent carcinogen and neurotoxin that is mainly formed by the Maillard
reaction of asparagine with starch at high temperatures. In this work, a food safety …

Asparagine is a non-essential amino acid since it can either be taken up via the diet or
synthesized by asparagine synthetase. Acute lymphoblastic leukemia (ALL) cells do not …

Over the past few years, there has been a surge in the industrial production of recombinant
enzymes from microorganisms due to their catalytic characteristics being highly efficient …

Asparaginase has been traditionally applied for only treating acute lymphoblastic leukemia
due to its ability to deplete asparagine. However, its ultimate anticancer potential for treating …

Abstract L-asparaginase (L-ASNase) is a life-saving medication used in the treatment of
Acute Lymphoblastic Leukemia (ALL) which affects over 60,000 people yearly. However, L …