Application of solid‐phase microextraction in current biomedical research

A Roszkowska, N Miękus… - Journal of separation …, 2019 - Wiley Online Library
Extraction of endogenous compounds and drugs and their corresponding metabolites from
complex matrices, such as biofluids and solid tissues, requires adequate analytical …

Advances in the microbial synthesis of the neurotransmitter serotonin

Y Wang, Y Chen, A Zhang, K Chen… - Applied Microbiology and …, 2023 - Springer
Serotonin, as a monoamine neurotransmitter, modulates the activity of the nervous system.
Due to its importance in the coordination of movement and regulation of mood, impairments …

Recent developments of bioanalytical methods in determination of neurotransmitters in vivo

J Matys, B Gieroba, K Jóźwiak - Journal of Pharmaceutical and Biomedical …, 2020 - Elsevier
Neurotransmitters (NTs) constitute an important group of messenger molecules and their
imbalance lead to various neurological disorders, making their analytical determination of …

UPLC-MS/MS assay for the simultaneous determination of catecholamines and their metabolites at low pg/mg in rat/mouse striatum

Y Lin, K Spiller, R Aras, W Jian - Journal of Pharmaceutical and Biomedical …, 2022 - Elsevier
Catecholamines and their metabolites act as neurotransmitters in the brain and are
important for nervous system function. In the current work, a highly selective and sensitive …

Advances in the metabolic engineering of Escherichia coli for the production of serotonin and its precursor, tryptophan

D Li, F Tan, CSK Lin, Y Liu, J Liu, C Gao - Biochemical Engineering …, 2024 - Elsevier
Serotonin, a monoamine neurotransmitter, participates in signal transduction in the nervous
systems of organisms. It is essential in the coordination of movement and regulation of …

[HTML][HTML] Extraction and preconcentration of compounds from the l-tyrosine metabolic pathway prior to their micellar electrokinetic chromatography separation

N Miękus, A Plenis, M Rudnicka… - … of Chromatography A, 2020 - Elsevier
The prominent biological effects of adrenaline (A), noradrenaline (NA) and dopamine (DA)
as well as the clinical importance of their metabolites (such as dihydroxyphenylacetic acid …

Solid‐phase extraction and clean‐up procedures in pharmaceutical analysis

P Campíns‐Falcó, A Sevillano‐Cabeza… - Encyclopedia of …, 2006 - Wiley Online Library
Solid‐phase extraction (SPE) using small cartridges filled with sorbents of a small particle
size has rapidly established itself as an important sample clean‐up technique. It has …

Hyphenated liquid chromatography techniques in analysis of neurotransmitters and their metabolites

B Gieroba, J Matys, K Jóźwiak - Liquid Chromatography, 2023 - Elsevier
Neurotransmitters are signaling molecules of crucial importance for proper functioning of the
nervous and other systems. Quantification of neurotransmitters is particularly difficult due to …

Ameliorative role of melatonin on CA1 of hippocampus and frontal cortex in induced social isolation in adult male albino rat

EM HAMOUD - The Medical Journal of Cairo University, 2019 - mjcu.journals.ekb.eg
Abstract Background: Social Isolation (SI) which means absence or insufficient contact with
others is a key factor in psychiatric disorders development, which might be necessary for …

[PDF][PDF] Pseudotargeted metabolomics for exploring the changes of neurotransmitters profile in aging rat brain and the potential neuroprotective effect of alkaloids from …

SW Li, YS Wu, SF Wu - Executive editor: Shan-Shan Lin …, 2022 - tmrjournals.com
Background: Aging is an essential risk factor for most neurodegenerative diseases,
including Alzheimer's disease and Parkinson's disease. However, changes in the levels of …