A role for microfluidic systems in precision medicine

JM Ayuso, M Virumbrales-Muñoz, JM Lang… - Nature …, 2022 - nature.com
Precision oncology continues to challenge the “one-size-fits-all” dogma. Under the precision
oncology banner, cancer patients are screened for molecular tumor alterations that predict …

Recent advances in 3D printing of biomedical sensing devices

MA Ali, C Hu, EA Yttri, R Panat - Advanced functional materials, 2022 - Wiley Online Library
Additive manufacturing, also called 3D printing, is a rapidly evolving technique that allows
for the fabrication of functional materials with complex architectures, controlled …

Recent advances in nanomaterial-based optical biosensors for food safety applications: Ochratoxin-A detection, as case study

DI Meira, AI Barbosa, J Borges, RL Reis… - Critical Reviews in …, 2024 - Taylor & Francis
Global population growth tremendously impacts the global food industry, endangering food
safety and quality. Mycotoxins, particularly Ochratoxin-A (OTA), emerge as a food chain …

Microfluidic systems for cancer diagnostics

JL Garcia-Cordero, SJ Maerkl - Current opinion in biotechnology, 2020 - Elsevier
Highlights•Microfluidic platforms enable the analysis and detection of cancer biomarkers.•
Circulating tumor cells can be separated on-chip from whole blood using several …

Revolutionary Point‐of‐Care Wearable Diagnostics for Early Disease Detection and Biomarker Discovery through Intelligent Technologies

F Haghayegh, A Norouziazad, E Haghani… - Advanced …, 2024 - Wiley Online Library
Early‐stage disease detection, particularly in Point‐Of‐Care (POC) wearable formats,
assumes pivotal role in advancing healthcare services and precision‐medicine. Public …

Microfluidic devices for the detection of viruses: Aspects of emergency fabrication during the COVID-19 pandemic and other outbreaks

JA Berkenbrock… - Proceedings of the …, 2020 - royalsocietypublishing.org
Extensive testing of populations against COVID-19 has been suggested as a game-changer
quest to control the spread of this contagious disease and to avoid further disruption in our …

Biomarkers for point-of-care diagnosis of sepsis

A Teggert, H Datta, Z Ali - Micromachines, 2020 - mdpi.com
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. In 2017, almost 50 million cases of sepsis were recorded worldwide …

Application of centrifugal microfluidics in immunoassay, biochemical analysis and molecular diagnosis

Y Shi, P Ye, K Yang, J Meng, J Guo, Z Pan, W Zhao… - Analyst, 2021 - pubs.rsc.org
Rapid diagnosis plays a vital role in daily life and is effective in reducing treatment costs and
increasing curability, especially in remote areas with limited availability of resources. Among …

3D biosensors in advanced medical diagnostics of high mortality diseases

R Rebelo, AI Barbosa, D Caballero, IK Kwon… - Biosensors and …, 2019 - Elsevier
Cardiovascular diseases, cancer, and diabetes are high mortality diseases, which account
for almost two thirds of all deaths worldwide. Their early detection and continuous evaluation …

Direct vs mediated coupling of antibodies to gold nanoparticles: the case of salivary cortisol detection by lateral flow immunoassay

F Di Nardo, S Cavalera, C Baggiani… - … applied materials & …, 2019 - ACS Publications
Stable and efficient conjugates between antibodies and gold nanoparticles (GNP-Ab) are
sought to develop highly sensitive and robust biosensors with applications in medicine …