Anticancer potential of lichens' secondary metabolites
Lichens produce different classes of phenolic compounds, including anthraquinones,
xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed …
xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed …
[HTML][HTML] Unraveling the function of epithelial-mesenchymal transition (EMT) in colorectal cancer: Metastasis, therapy response, and revisiting molecular pathways
E Sabouni, MM Nejad, S Mojtabavi… - Biomedicine & …, 2023 - Elsevier
Colorectal cancer (CRC) is a dangerous form of cancer that affects the gastrointestinal tract.
It is a major global health concern, and the aggressive behavior of tumor cells makes it …
It is a major global health concern, and the aggressive behavior of tumor cells makes it …
Cancer metabolism control by natural products: Pyruvate kinase M2 targeting therapeutics
AH El‐Far, SK Al Jaouni, X Li, J Fu - Phytotherapy Research, 2022 - Wiley Online Library
Glycolysis is the primary source of energy for cancer growth and metastasis. The shift in
metabolism from mitochondrial oxidative phosphorylation to aerobic glycolysis is called the …
metabolism from mitochondrial oxidative phosphorylation to aerobic glycolysis is called the …
Bioactive lichen secondary metabolites and their presence in species from Chile
E Poulsen-Silva, F Gordillo-Fuenzalida, C Atala… - Metabolites, 2023 - mdpi.com
Lichens are symbiotic organisms composed of at least one fungal and one algal species.
They are found in different environments around the world, even in the poles and deserts …
They are found in different environments around the world, even in the poles and deserts …
In Vitro Anticancer Activity and Oxidative Stress Biomarkers Status Determined by Usnea barbata (L.) FH Wigg. Dry Extracts
Lichens represent an important resource for common traditional medicines due to their
numerous metabolites that can exert diverse pharmacological activities including anticancer …
numerous metabolites that can exert diverse pharmacological activities including anticancer …
Modulation of hypoxia-inducible factor-1 signaling pathways in cancer angiogenesis, invasion, and metastasis by natural compounds: a comprehensive and critical …
Tumor cells employ multiple signaling mediators to escape the hypoxic condition and trigger
angiogenesis and metastasis. As a critical orchestrate of tumorigenic conditions, hypoxia …
angiogenesis and metastasis. As a critical orchestrate of tumorigenic conditions, hypoxia …
Physciosporin suppresses mitochondrial respiration, aerobic glycolysis, and tumorigenesis in breast cancer
Background Physciosporin (PHY) is one of the potent anticancer lichen compound.
Recently, PHY was shown to suppress colorectal cancer cell proliferation, motility, and …
Recently, PHY was shown to suppress colorectal cancer cell proliferation, motility, and …
Libertellenone T, a novel compound isolated from endolichenic fungus, induces G2/M phase arrest, apoptosis, and autophagy by activating the ROS/JNK pathway in …
CDB Gamage, JH Kim, Y Yang, İ Taş, SY Park, R Zhou… - Cancers, 2023 - mdpi.com
Simple Summary Libertellenone T (B) is a natural product derived from the secondary
metabolites of the endolichenic fungus, Pseudoplectania sp. In this study, we investigated …
metabolites of the endolichenic fungus, Pseudoplectania sp. In this study, we investigated …
1′-O-methyl-averantin isolated from the endolichenic fungus Jackrogersella sp. EL001672 suppresses colorectal cancer stemness via sonic Hedgehog and Notch …
Endolichenic fungi are host organisms that live on lichens and produce a wide variety of
secondary metabolites. Colorectal cancer stem cells are capable of self-renewal and …
secondary metabolites. Colorectal cancer stem cells are capable of self-renewal and …
Lichens as a repository of bioactive compounds: an open window for green therapy against diverse cancers
Lichens, algae and fungi-based symbiotic associations, are sources of many important
secondary metabolites, such as antibiotics, anti-inflammatory, antioxidants, and anticancer …
secondary metabolites, such as antibiotics, anti-inflammatory, antioxidants, and anticancer …