Adipose tissue, colloquially known as" fat," is an extraordinarily flexible and heterogeneous
organ. While historically viewed as a passive site for energy storage, we now appreciate that …

The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …

The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

De novo lipogenesis (DNL) is a complex and highly regulated process in which
carbohydrates from circulation are converted into fatty acids that are then used for …

Obesity, which is a worldwide epidemic, confers increased risk for multiple serious
conditions including type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular …

Obesity increases the risk for metabolic, cardiovascular, chronic inflammatory, and several
malignant diseases and, therefore, may contribute to shortened lifespan. Adipokines are …

Obesity is currently the most extended metabolic disturbance worldwide favoring the
development of cardiometabolic alterations such as type 2 diabetes, hypertension, and …

Mature adipocytes store fatty acids and are a common component of tissue stroma.
Adipocyte function in regulating bone marrow, skin, muscle, and mammary gland biology is …

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide, and
a major cause of liver cirrhosis and hepatocellular carcinoma. NAFLD is intimately linked …

Non-alcoholic fatty liver disease (NAFLD) is a major global health threat due to its growing
incidence and prevalence. It is becoming the leading cause of liver disease in addition to its …