Behçet syndrome: a contemporary view

H Yazici, E Seyahi, G Hatemi, Y Yazici - Nature Reviews Rheumatology, 2018 - nature.com
The presence of symptom clusters, regional differences in disease expression and
similarities with, for example, Crohn's disease suggest multiple pathological pathways are …

Immunopathogenesis of Behcet's disease

B Tong, X Liu, J Xiao, G Su - Frontiers in immunology, 2019 - frontiersin.org
Behcet's disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology
characterized by recurrent episodes of oral aphthous ulcers, genital ulcers, skin lesions …

Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations

S Kalra, A Silman, G Akman-Demir, S Bohlega… - Journal of …, 2014 - Springer
Neuro-Behçet's disease (NBD) is one of the more serious manifestations of Behçet's disease
(BD), which is a relapsing inflammatory multisystem disease with an interesting …

Neuro-Behçet's disease: epidemiology, clinical characteristics, and management

A Al-Araji, DP Kidd - The Lancet Neurology, 2009 - thelancet.com
Behçet's disease (BD) is a multisystem relapsing inflammatory disorder of unknown cause.
In neuro-BD (NBD), the CNS can be involved in one or both of two ways: first, and most …

New insights into the pathogenesis of Behcet's disease

MP de Chambrun, B Wechsler, G Geri, P Cacoub… - Autoimmunity …, 2012 - Elsevier
Behçet's disease (BD) is a recurrent systemic inflammatory disorder of unknown origin
characterized by oral and genital mucous ulcer, uveitis, and skin lesions. Involvement of …

Cytokines and Behcet's disease

ZY Zhou, SL Chen, N Shen, Y Lu - Autoimmunity reviews, 2012 - Elsevier
Behcet's Disease (BD) is a systemic vasculitis of unknown etiology. Increasing studies find
that a sophisticated interlacing cytokine network is closely implicated in the onset, evolution …

Anakinra treatment in drug-resistant Behcet's disease: a case series

L Cantarini, A Vitale, P Scalini, CA Dinarello… - Clinical …, 2015 - Springer
The study objective was to report treatment with an interleukin (IL)-1 receptor antagonist,
anakinra, in patients with multiorgan Behcet's disease (BD). Comparison of clinical …

Effectiveness of tocilizumab in Behcet's disease: a systematic literature review

M Akiyama, Y Kaneko, T Takeuchi - Seminars in Arthritis and Rheumatism, 2020 - Elsevier
Objective Behcet's disease is a systemic disorder with ocular, mucocutaneous, and vascular
involvement. The efficacy of tumor necrosis factor inhibition has been established; however …

Neuro-Behçet syndrome

S Saip, G Akman-Demir, A Siva - Handbook of clinical neurology, 2014 - Elsevier
Behçet syndrome (BS) is an idiopathic chronic relapsing multisystem vascular-inflammatory
disease of unknown origin. As the disease affects many organs and systems and shows a …

Interleukin 6 and cognitive dysfunction

I Trapero, O Cauli - Metabolic brain disease, 2014 - Springer
Abstract The interleukin-6 (IL-6) is a pleiotropic cytokine that plays a key role in interaction
between immune and nervous system. Although IL-6 has neurotrophic properties and …