Genomics-based precision medicine has revolutionized oncology but also has inherent
limitations. Functional precision oncology is emerging as a complementary approach that …

Immune checkpoint therapies (ICT) can reinvigorate the effector functions of anti-tumour T
cells, improving cancer patient outcomes. Anti-tumour T cells are initially formed during their …

Recent technological advancements in testing and monitoring instrumentation have greatly
contributed to the progress in cancer treatment by surgical, chemotherapeutic and …

Cancer immunotherapy has achieved remarkable success over the past decade by
modulating patients' own immune systems and unleashing pre-existing immunity. However …

The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

Simple Summary The clinical success of cancer immunotherapy targeting immune
checkpoints (eg, PD-1, CTLA-4) has ushered in a new era of cancer therapeutics aimed at …

With the ability to cross biological barriers, encapsulate and efficiently deliver drugs and
nucleic acid therapeutics, and protect the loaded cargos from degradation, different soft …

Recently, considerable interest has emerged in the development of biosensors to detect
biomarkers and immune checkpoints to identify and measure cancer through liquid biopsies …

Cytokine production analysis at the single-cell level, such as detection of type I interferon
(IFN-I), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) producing cells, is …

Anti-PD1 immune checkpoint blockade (ICB) has shown promising results for treating
several aggressive cancers, enhancing patient survival rates. The variability in clinical …