In silico evaluation of binding of 2-deoxy-D-glucose with mpro of nCoV to combat COVID-19

APS Raman, K Kumari, P Jain, VK Vishvakarma… - Pharmaceutics, 2022 - mdpi.com
COVID-19 has threatened the existence of humanity andthis infection occurs due to SARS-
CoV-2 or novel coronavirus, was first reported in Wuhan, China. Therefore, there is a need …

An insight for the interaction of drugs (acyclovir/ganciclovir) with various ionic liquids: DFT calculations and molecular docking

A Kumar, K Kumari, APS Raman, P Jain… - Journal of Physical …, 2022 - Wiley Online Library
Since December 2019, the humanity is in trouble due to the huge infection of SARS‐CoV‐2
and caused COVID‐19, named by WHO. Therefore, researchers and health care …

Exploration of DFT and TD-DFT computation to investigate the interaction between paracetamol and lithium or its compounds

MB Singh, P Bhagat, P Jain, P Singh - Journal of Molecular Liquids, 2023 - Elsevier
Paracetamol is a commonly used antipyretic drug and its consumption drastically was
increased during the COVID-19 times as fever was one of the symptoms. The excessive …

Volumetric and acoustic properties of L-phenyl glycine and L-phenylalanine in aqueous solution of 1-dodecyl-3-methylimidazolium bromide [C12mim][Br]

R Sharma, H Kumar, M Singla, V Kumar… - Journal of Molecular …, 2022 - Elsevier
To study the molecular interactions between the ternary mixtures containing long chain
imidazolium based ionic liquid as a common solvent with substituted amino acids L-phenyl …

Investigate the binding of pesticides with the TLR4 receptor protein found in mammals and zebrafish using molecular docking and molecular dynamics simulations

S Yadav, M Aslam, A Prajapat, I Massey, B Nand… - Scientific Reports, 2024 - nature.com
The widespread use of pesticides poses significant threats to both environmental and
human health, primarily due to their potential toxic effects. The study investigated the …

Exploration of interactions between L-aspartic acid and saccharides in aqueous medium at T=(293.15–313.15) K: Physicochemical and spectroscopic approach

RK Pradhan, S Singh - Journal of Molecular Liquids, 2024 - Elsevier
In this study, we report the density, viscosity, taste behavior and UV–Vis spectrophotometry
results of L-Aspartic acid (Asp) in aqueous solutions of L-arabinose and D-xylose over an …

Exploring the effects of saccharides on the solvation behaviour of L-Citrulline in aqueous medium: Volumetric, transition state theory, transfer parameters and …

RK Pradhan, S Singh - Food Chemistry, 2024 - Elsevier
This study examines the volumetric, viscometric and UV–vis characteristics of L-Citrulline in
water and aqueous saccharides at atmospheric pressure across the whole concentration …

Study the solubility of pharmaceutical ingredients and their eutectic mixtures: An in-depth density functional theory and molecular dynamics simulations approaches

M Aslam, G Pandey, N Deshwal, A Kumar… - Journal of Molecular …, 2024 - Elsevier
Solubility is a major concern for many active pharmaceutical ingredients (APIs) and drugs.
Owing to their better solubility, biodegradability and low toxicity of APIs and drugs, eutectic …

Probing into Volumetric and Acoustic Properties of Aqueous l-Ascorbic Acid in the Presence of Diammonium Hydrogen Phosphate and Potassium Chloride

P Mohapatra, S Mohapatra, MP Panda… - Journal of Chemical & …, 2024 - ACS Publications
The objective of this study is to investigate the effects of residual present-day high-grade
fertilizers on human physiology. Volumetric and acoustic investigations on aqueous l …

Investigating the Potential of 2‐Ethylbutyl‐(Phenoxy) phosphoryl‐D‐Alaninate Against RNA‐Dependent RNA Polymerase (RdRp) of SARS‐CoV‐2

S Yadav, D Kumar, H Chopra, I Bhatt… - Chemistry & …, 2024 - Wiley Online Library
There was an emergency call globally when COVID‐19 was detected in December 2019.
The SARS‐CoV‐2 virus, a modified virus, is what causes this contagious disease. Although …