Targeted delivery of oligonucleotides to liver hepatocytes using N-acetylgalactosamine
(GalNAc) conjugates that bind to the asialoglycoprotein receptor has become a …

Cancer, infectious diseases, and metabolic and hereditary genetic disorders are a global
health burden affecting millions of people, with contemporary treatments offering limited …

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, and is
related to fatal and non-fatal liver, metabolic, and cardiovascular complications. Its non …

Conclusions Comorbidities, including coronary artery disease, cerebrovascular disease and
chronic obstructive pulmonary disease, are more prevalent in hospitalized Chinese patients …

Non-alcoholic fatty liver disease (NAFLD), or metabolic (dysfunction)-associated fatty liver
disease (MAFLD), is characterized by high global incidence and prevalence, a tight …

Alternative RNA splicing is a process by which introns are removed and exons are
assembled to construct different RNA transcript isoforms from a single pre-mRNA. Previous …

Breast cancer (BC) is considered the leading cause of mortality and morbidity among adult
women worldwide, and it is associated with many genetic or hormonal factors. Despite the …

NAFLD and its inflammatory condition NASH, which is more likely to progress to fibrosis and
advanced liver disease, are the histologic manifestation of a heterogeneous disease closely …

Background: NAFLD has become the leading cause of chronic liver disease worldwide
afflicting about one quarter of the adult population. NASH is a severe subtype of NAFLD …

The prevalence of NAFLD (non-alcoholic fatty liver disease) is a rapidly increasing problem,
affecting a huge population around the globe. However, CVDs (cardiovascular diseases) …