White matter injury in the preterm infant: pathology and mechanisms

SA Back - Acta neuropathologica, 2017 - Springer
The human preterm brain is particularly susceptible to cerebral white matter injury (WMI) that
disrupts the normal progression of developmental myelination. Advances in the care of …

The early development of brain white matter: a review of imaging studies in fetuses, newborns and infants

J Dubois, G Dehaene-Lambertz, S Kulikova, C Poupon… - neuroscience, 2014 - Elsevier
Studying how the healthy human brain develops is important to understand early
pathological mechanisms and to assess the influence of fetal or perinatal events on later life …

Procedural pain and brain development in premature newborns

S Brummelte, RE Grunau, V Chau, KJ Poskitt… - Annals of …, 2012 - Wiley Online Library
Objective: Preterm infants are exposed to multiple painful procedures in the neonatal
intensive care unit (NICU) during a period of rapid brain development. Our aim was to …

Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances

JJ Volpe - The Lancet Neurology, 2009 - thelancet.com
Brain injury in premature infants is of enormous public health importance because of the
large number of such infants who survive with serious neurodevelopmental disability …

[HTML][HTML] Neonatal pain in very preterm infants: long-term effects on brain, neurodevelopment and pain reactivity

RE Grunau - Rambam Maimonides medical journal, 2013 - ncbi.nlm.nih.gov
Abstract Effects of early life psychosocial adversity have received a great deal of attention,
such as maternal separation in experimental animal models and abuse/neglect in young …

Brain injury in premature neonates: a primary cerebral dysmaturation disorder?

SA Back, SP Miller - Annals of neurology, 2014 - Wiley Online Library
With advances in neonatal care, preterm neonates are surviving with an evolving
constellation of motor and cognitive disabilities that appear to be related to widespread …

Neonatal brain injury

DM Ferriero - New England Journal of Medicine, 2004 - Mass Medical Soc
More than 95 percent of infants who have neonatal stroke survive to adulthood, and many
have residual motor or cognitive disabilities. This article makes the point that recognition of …

[HTML][HTML] Abnormal brain development in newborns with congenital heart disease

SP Miller, PS McQuillen, S Hamrick, D Xu… - … England Journal of …, 2007 - Mass Medical Soc
Background Congenital heart disease in newborns is associated with global impairment in
development. We characterized brain metabolism and microstructure, as measures of brain …

The encephalopathy of prematurity—brain injury and impaired brain development inextricably intertwined

JJ Volpe - Seminars in pediatric neurology, 2009 - Elsevier
The field of neonatal neurology, and specifically its focus on the premature infant, had its
inception in neuropathologic studies. Since then, the development of advanced imaging …

Neonatal pain-related stress predicts cortical thickness at age 7 years in children born very preterm

M Ranger, CMY Chau, A Garg, TS Woodward, MF Beg… - PloS one, 2013 - journals.plos.org
Background Altered brain development is evident in children born very preterm (24–32
weeks gestational age), including reduction in gray and white matter volumes, and thinner …