Oxytocin mitigated the depressive-like behaviors of maternal separation stress through modulating mitochondrial function and neuroinflammation
H Amini-Khoei, A Mohammadi-Asl, S Amiri… - Progress in Neuro …, 2017 - Elsevier
Mother-infant contact has a critical role on brain development and behavior. Experiencing
early-life adversities (such as maternal separation stress or MS in rodents) results in …
early-life adversities (such as maternal separation stress or MS in rodents) results in …
[HTML][HTML] Tiagabine suppresses pentylenetetrazole-induced seizures in mice and improves behavioral and cognitive parameters by modulating BDNF/TrkB expression …
Abstract Tiagabine (Tia), a new-generation antiseizure drug that mimics the GABAergic
signaling by inhibiting GABA transporter type-1, is the least studied molecule in chronic …
signaling by inhibiting GABA transporter type-1, is the least studied molecule in chronic …
[HTML][HTML] What is the Role of Lithium in Epilepsy?
Lithium is a well-known FDA-approved treatment for bipolar and mood disorders. Lithium
has been an enigmatic drug with multifaceted actions involving various neurotransmitters …
has been an enigmatic drug with multifaceted actions involving various neurotransmitters …
[HTML][HTML] Involvement of opioid system in behavioral despair induced by social isolation stress in mice
A Haj-Mirzaian, R Nikbakhsh, K Ramezanzadeh… - Biomedicine & …, 2019 - Elsevier
Social isolation stress (SIS) as a type of chronic stress could induce depressive-and anxiety-
like behaviors. Our study evaluates the role of opioid system on negative behavioral impacts …
like behaviors. Our study evaluates the role of opioid system on negative behavioral impacts …
Protective effect of minocycline on LPS-induced mitochondrial dysfunction and decreased seizure threshold through nitric oxide pathway
A Haj-Mirzaian, K Ramezanzadeh… - European journal of …, 2019 - Elsevier
Lipopolysaccharide (LPS) increases inflammatory cytokines of the brain and deregulates the
mitochondrial function, thus could increase the seizure susceptibility. Studies have shown …
mitochondrial function, thus could increase the seizure susceptibility. Studies have shown …
Implication of NMDA-NO pathway in the antidepressant-like effect of ellagic acid in male mice
Depression is one the common psychiatric disorders through the world. Nitric oxide (NO)
and N-methyl-d-aspartate receptor (NMDA-R) are involved in the pathophysiology of …
and N-methyl-d-aspartate receptor (NMDA-R) are involved in the pathophysiology of …
Ellagic acid through attenuation of neuro-inflammatory response exerted antidepressant-like effects in socially isolated mice
Recent studies have been demonstrated that neuroinflammation plays a crucial role in the
pathophysiology of depression. Therefore, anti-inflammatory medications could be regarded …
pathophysiology of depression. Therefore, anti-inflammatory medications could be regarded …
Therapeutic effects of minocycline pretreatment in the locomotor and sensory complications of spinal cord injury in an animal model
K Afshary, M Chamanara, B Talari, P Rezaei… - Journal of Molecular …, 2020 - Springer
Spinal cord injury (SCI) is known as a debilitating condition which usually occurs due to
traumas to the spine. However, the injury could also occur during clinical interventions such …
traumas to the spine. However, the injury could also occur during clinical interventions such …
Nitric oxide and glutamate are contributors of anti-seizure activity of rubidium chloride: a comparison with lithium
The neuro-protective effects of rubidium and lithium as alkali metals have been reported for
different central nervous system dysfunctions including mania and depression. The aim of …
different central nervous system dysfunctions including mania and depression. The aim of …
The anticonvulsant activity and cerebral protection of chronic lithium chloride via NMDA receptor/nitric oxide and phospho-ERK
The underlying mechanisms for the neuroprotective effects of lithium chloride in
neurodegenerative diseases such as seizures remain unknown. In present study the …
neurodegenerative diseases such as seizures remain unknown. In present study the …