Infections lacking precise diagnosis are often caused by a rare or uncharacterized
pathogen, a combination of pathogens, or a known pathogen carrying undocumented or …

Objectives This meta-analysis focused on systematically assessing the clinical value of
mNGS for infection in hematology patients. Methods We searched for studies that assessed …

Purpose We analyzed the clinical concordance of mNGS test results from blood samples
and improved the clinical efficiency of mNGS in the diagnosis of suspected sepsis …

Background Febrile neutropenia (FN) after chemotherapy is a major cause of morbidity
during cancer treatment. The performance of metagenomic next-generation sequencing …

The diagnosis of invasive pulmonary aspergillosis (IPA) diseases in non-neutropenic
patients remains challenging. It is essential to develop optimal non-invasive or minimally …

Chimeric antigen receptor-modified T cell (CAR-T) therapy is a promising novel
immunotherapy for hematologic malignancies, and the diagnosis of infection after CAR-T …

Introduction Conventional etiological detection and pathogenic antibody methods make it
challenging to identify the atypical pathogens among the community‐acquired pneumonia …

Introduction: Systematic evaluation of the diagnostic value of next generation sequencing
(NGS) in sepsis etiology. Methodology: We conducted a systematic search on four …

Introduction Metagenomic next-generation sequencing (mNGS) is a novel technique for
detecting pathogens. This retrospective study evaluated the diagnostic value of mNGS using …

Metagenomic next-generation sequencing (mNGS) has revolutionized the detection of
pathogens, particularly in immunocompromised individuals such as pediatric patients …