The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Diabetes Mellitus (DM) is a metabolic disorder that is spreading alarmingly around the
globe. Type-2 DM (T2DM) is characterized by low-grade inflammation and insulin resistance …

Type 2 diabetes mellitus (T2DM) patients are at a higher risk of developing Alzheimer's
disease (AD). Mounting evidence suggests the emerging important role of circadian rhythms …

Objective The development of effective anti-obesity therapeutics relies heavily on the ability
to target specific brain homeostatic and hedonic mechanisms controlling body weight. To …

Abstract Type 2 diabetes (T2DM) is a chronic metabolic disorder. Impaired insulin secretion,
enhanced hepatic glucose production, and suppressed peripheral glucose use are the main …

For decades, there have been observations demonstrating significant metabolic
disturbances in people with schizophrenia including clinically relevant weight gain …

Associated with important comorbidities that significantly reduce patients' overall wellbeing
and life expectancy, Cushing's disease (CD) is the most common cause of endogenous …

Atherosclerotic cardiovascular disease (ASCVD) is a major cause of morbidity and mortality
in both men and women with type 1 and type 2 diabetes. There are numerous risk factors …

Prolactin (PRL) has roles in various physiological functions. Although experimental studies
showed that PRL has both beneficial and adverse effects on type 2 diabetes mellitus, clinical …

Dopamine signalling is a crucial part of the brain reward system and can affect feeding
behaviour. Dopamine receptors are also expressed in the hypothalamus, which is known to …