Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
Role of exosomal proteins in cancer diagnosis
W Li, C Li, T Zhou, X Liu, X Liu, X Li, D Chen - Molecular cancer, 2017 - Springer
Exosomes are emerging as a new type of cancer biomarkers. Exosome is a bilayered nano-
sized vesicle secreted by various living cells in all body fluids. Based on the expanding …
sized vesicle secreted by various living cells in all body fluids. Based on the expanding …
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
Urine is commonly used for clinical diagnosis and biomedical research. The discovery of
extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last …
extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last …
Identifying high-grade serous ovarian carcinoma–specific extracellular vesicles by polyketone-coated nanowires
Cancer cell–derived extracellular vesicles (EVs) have unique protein profiles, making them
promising targets as disease biomarkers. High-grade serous ovarian carcinoma (HGSOC) is …
promising targets as disease biomarkers. High-grade serous ovarian carcinoma (HGSOC) is …
Liquid biopsy: a step forward towards precision medicine in urologic malignancies
A Di Meo, J Bartlett, Y Cheng, MD Pasic, GM Yousef - Molecular cancer, 2017 - Springer
There is a growing trend towards exploring the use of a minimally invasive “liquid biopsy” to
identify biomarkers in a number of cancers, including urologic malignancies. Multiple …
identify biomarkers in a number of cancers, including urologic malignancies. Multiple …
Exosomes: novel biomarkers for clinical diagnosis
J Lin, J Li, B Huang, J Liu, X Chen… - The scientific world …, 2015 - Wiley Online Library
Exosomes are 30–120 nm endocytic membrane‐derived vesicles that participate in cell‐to‐
cell communication and protein and RNA delivery. Exosomes harbor a variety of proteins …
cell communication and protein and RNA delivery. Exosomes harbor a variety of proteins …
Proteomics of extracellular vesicles: exosomes and ectosomes
Almost all bacteria, archaea, and eukaryotic cells shed extracellular vesicles either
constitutively or in a regulated manner. These nanosized membrane vesicles are spherical …
constitutively or in a regulated manner. These nanosized membrane vesicles are spherical …
Liquid biopsies, novel approaches and future directions
A Armakolas, M Kotsari, J Koskinas - Cancers, 2023 - mdpi.com
Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …
Evidence-based clinical use of nanoscale extracellular vesicles in nanomedicine
Recent research has demonstrated that all body fluids assessed contain substantial
amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by …
amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by …
Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications
Cell to cell communication is essential for the coordination and proper organization of
different cell types in multicellular systems. Cells exchange information through a multitude …
different cell types in multicellular systems. Cells exchange information through a multitude …