Neutrophils are immune cells with unusual biological features that furnish potent
antimicrobial properties. These cells phagocytose and subsequently kill prokaryotic and …

Metabolism is one of the strongest drivers of interkingdom interactions—including those
between microorganisms and their multicellular hosts. Traditionally thought to fuel energy …

Metastasis is the leading cause of cancer-related deaths, and obesity is associated with
increased breast cancer (BC) metastasis. Preclinical studies have shown that obese …

Sudden cardiac death, arising from abnormal electrical conduction, occurs frequently in
patients with coronary heart disease. Myocardial ischemia simultaneously induces …

Iron is an essential element for all microorganisms. Siderophores are low-weight, high-
affinity iron chelating molecules produced in response to iron deficiency by Gram-positive …

Neutrophil extracellular traps (NETs) have an important role during infection by helping
neutrophils to capture and kill pathogens. However, evidence is accumulating that …

Iron is necessary for the survival of almost all aerobic organisms. In the mammalian host,
iron is a required cofactor for the assembly of functional iron-sulfur (Fe-S) cluster proteins …

Elucidating the benefits of individual microbiota-derived molecules in host animals is
important for understanding the symbiosis between humans and their microbiota. The …

Iron is a transition metal utilized by nearly all forms of life for essential cellular processes,
such as DNA synthesis and cellular respiration. During infection by bacterial pathogens, the …

The acute-phase response is triggered by the presence of infectious agents and danger
signals which indicate hazards for the integrity of the mammalian body. One central feature …