Azetidines are prominent structural scaffolds in bioactive molecules, medicinal chemistry,
and ligand design for transition metals. However, state-of-the-art methods cannot be applied …

We disclose a transition-metal-free NaI/PPh3-mediated direct C–H alkylation of azauracils
using N-(acyloxy) pthalimides (NHPIs) as readily available alkyl surrogates under visible …

Chemical modification of nucleotides can improve the metabolic stability and target
specificity of oligonucleotide therapeutics, and alkylphosphonates have been employed as …

Exploiting β-scission in aminophosphoranyl radicals for radical-mediated transformations
has been a longstanding challenge. In this study, we investigated the untapped potential of …

Cyclization reactions provide an instant and effective path to generate mono-and polycyclic
systems and are one of the most important and fundamental fields in organic chemistry …

The rapid assembly of valuable cyclic amine architectures in a single step from simple
precursors has been recognized as an ideal platform in term of efficiency and sustainability …

A general catalytic donor for the combination of a photoinduced electron donor–acceptor
(EDA) complex and energy transfer was developed. This mild and metal-free protocol allows …

Herein, we report a photoredox nucleophilic (radio) fluorination using TEMPO-derived
alkoxyamines, a class of substrates accessible in a single step from a diversity of readily …

A decarboxylative C (sp2)–C (sp3) cross-coupling reaction of α-oxy carboxylic acids using
dual nickel/photoredox catalysis has been developed for the synthesis of complex …

Current methodologies for the functionalization of [1.1. 1] propellane primarily focus on
achieving 1, 3-difunctionalized bicyclo [1.1. 1] pentane or ring-opened cyclobutane moiety …