Crocus sativus L.(saffron) is widely used as a traditional spice for flavoring, coloring and
medicinal purposes. As a traditional Chinese herb, saffron promotes blood circulation …

Crocus sativus L.(saffron) appears to own neuroprotective effects on cognitive impairment in
patients with Alzheimer's disease (AD). The purpose of this work is to review evidence and …

Oxidative stress plays an important role in the development of Alzheimer's disease (AD). The
purpose of this study was to investigate the protective effects of lutein, a carotenoid with …

Crocins, as a kind of water-soluble carotenoid pigment, are a series of ester compounds
formed from crocetin and gentibiose or glucose, and mainly distributed among Crocus …

Recent evidence demonstrates that Crocus sativus L.(saffron) counteracts oxidative stress,
mitochondrial dysfunction and neuroinflammation, closely linked to initiation and …

Protein misfolding diseases (PMDs) are chronic and progressive, with no effective therapy
so far. Aggregation and misfolding of amyloidogenic proteins are closely associated with the …

Brain inflammation is associated with cognitive dysfunction, especially in elderly.
Trigonelline is a plant alkaloid and a major component of coffee and fenugreek with anti …

Organophosphorus compounds are widely used in agriculture. Epidemiological studies
propose that pesticide exposure is a risk factor for Alzheimer's disease (AD), but the …

Objective: While stress reportedly impairs memory, saffron enhances it. This study
investigated the therapeutic effects of saffron extract on different memory types, anxiety-like …

As a valuable medicinal and edible plant, Crocus sativus L. has had wide applications since
ancient times. Herein, a comprehensive approach for characterization of constituents in …