Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Candida albicans is a common fungal pathogen of humans that colonizes the skin and
mucosal surfaces of most healthy individuals. Until recently, little was known about the …

The interaction between Candida albicans and its host cells is characterized by a complex
interplay between the expression of fungal virulence factors, which results in adherence …

Dendritic cells (DCs) are central in the orchestration of the various forms of immunity and
tolerance. Their immunoregulatory role mainly relies on the ligation of specific receptors that …

Mucocutaneous fungal infections are typically found in patients who have no known immune
defects. We describe a family in which four women who were affected by either recurrent …

Abstract β-Glucan is one of the most abundant polysaccharides in fungal pathogens, yet its
importance in antifungal immunity is unclear. Here we show that deficiency of dectin-1, the …

The innate immune response was once considered to be a limited set of responses that
aimed to contain an infection by primitive'ingest and kill'mechanisms, giving the host time to …

Dendritic cells (DCs) are crucial in the defence against pathogens. Invading pathogens are
recognized by Toll-like receptors (TLRs) and receptors such as C-type lectins expressed on …