Approaches to limit systemic antibiotic use in acne: systemic alternatives, emerging topical therapies, dietary modification, and laser and light-based treatments

JS Barbieri, N Spaccarelli, DJ Margolis… - Journal of the American …, 2019 - Elsevier
Acne is one of the most common diseases worldwide and affects∼ 50 million individuals in
the United States. Oral antibiotics are the most common systemic agent prescribed for the …

Oral isotretinoin for the treatment of dermatologic conditions other than acne: a systematic review and discussion of future directions

S Chu, L Michelle, C Ekelem, CT Sung, N Rojek… - Archives of …, 2021 - Springer
While isotretinoin has been the gold-standard of therapy for severe acne since its approval
in 1982, its anti-inflammatory properties makes it a potentially applicable and versatile …

[HTML][HTML] Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

A Oláh, BI Tóth, I Borbíró, K Sugawara… - The Journal of …, 2014 - Am Soc Clin Investig
The endocannabinoid system (ECS) regulates multiple physiological processes, including
cutaneous cell growth and differentiation. Here, we explored the effects of the major …

A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars

A Stella, B Palmieri, C Laurino… - La Clinica Terapeutica, 2019 - clinicaterapeutica.it
Objective To investigate the therapeutic effect of CBD-ointment administered on severe skin
chronic diseases and/or on their outcome scars. Methods A spontaneous, anecdotal …

Differential effectiveness of selected non‐psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne …

A Oláh, A Markovics, J Szabó‐Papp… - Experimental …, 2016 - Wiley Online Library
Acne is a common skin disease characterized by elevated sebum production and
inflammation of the sebaceous glands. We have previously shown that a non‐psychotropic …

[HTML][HTML] Diagnosis and treatment of acne

S Feldman, RE Careccia, KL Barham… - American Family …, 2004 - aafp.org
Acne can cause significant embarrassment and anxiety in affected patients. It is important for
family physicians to educate patients about available treatment options and their expected …

Effectiveness of conventional, low‐dose and intermittent oral isotretinoin in the treatment of acne: a randomized, controlled comparative study

JW Lee, KH Yoo, KY Park, TY Han, K Li… - British Journal of …, 2011 - academic.oup.com
Background The efficacy of conventional isotretinoin treatment (0· 5–1· 0 mg kg− 1 daily for
16–32 weeks, reaching a cumulative dose of 120 mg kg− 1) for acne has been well …

Preventing and managing the side effects of isotretinoin

M Brelsford, TC Beute - , 27, 3, 2008 - ingentaconnect.com
Isotretinoin (13-cis-retinoic acid) is widely used for the treatment of severe acne as well as
for disorders of conification, for psoriasis, and for skin cancer prevention. As a member of the …

[HTML][HTML] Resistin-like molecule α provides vitamin-A-dependent antimicrobial protection in the skin

TA Harris, S Gattu, DC Propheter, Z Kuang, S Bel… - Cell host & …, 2019 - cell.com
Vitamin A deficiency increases susceptibility to skin infection. However, the mechanisms by
which vitamin A regulates skin immunity remain unclear. Here, we show that resistin-like …

Acne: systemic treatment

A Katsambas, A Papakonstantinou - Clinics in dermatology, 2004 - Elsevier
Acne vulgaris is a disease affecting mostly adolescents and young adults that, when severe,
has the potential to result in scarring and permanent disfigurement. Systemic treatment is …