Oxidative stress is a reflection of the imbalance between the production of reactive oxygen
species (ROS) and the scavenging capacity of the antioxidant system. Excessive ROS …

There have been considerable recent advances towards a better understanding of the
complex cellular and molecular network underlying liver fibrogenesis. Recent data indicate …

Mesenchymal stem cells (MSCs) have been considered as an attractive tool for the therapy
of diseases. Exosomes excreted from MSCs can reduce myocardial ischemia/reperfusion …

This review summarizes the literature describing the molecular mechanisms of arsenic-
induced oxidative stress, its relevant biomarkers, and its relation to various diseases …

Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

Apoptosis is a prominent feature of liver diseases. Causative factors such as alcohol,
viruses, toxic bile acids, fatty acids, drugs, and immune response, can induce apoptotic cell …

Liver fibrosis is the pathological process of excessive extracellular matrix deposition after
liver injury and is a precursor to cirrhosis, hepatocellular carcinoma (HCC). It is essentially a …

Thioacetamide (TAA) undergoes bioactivation in the liver by the CYP450 2E1 enzyme,
resulting in the formation of TAA-S-oxide and TAA-S-dioxide. TAA-S-dioxide induces …

Currently, the most effective treatment for end-stage liver fibrosis is liver transplantation;
however, transplantation is limited by a shortage of donor organs, surgical complications …

Mulberrin (Mul) is a key component of the traditional Chinese medicine Romulus Mori with
various biological functions. However, the effects of Mul on liver fibrosis have not been …