ABSTRACT Introduction: Aicardi-Goutières syndrome (AGS) is the prototype of the type I
interferonopathies, a new heterogeneous group of autoinflammatory disorders in which type …

In recent years, several paramyxoviruses have emerged to infect humans, including
previously unidentified zoonoses. Hendra and Nipah viruses (henipaviruses within this …

Renal fibrosis is a typical pathological change in chronic kidney disease (CKD). Epithelial-
mesenchymal transition (EMT) is the predominant stage. Activation of macroautophagy …

Numerous loss-of-function mutations in the progranulin (GRN) gene cause frontotemporal
lobar degeneration with ubiquitin and TAR–DNA binding protein 43-positive inclusions by …

Acetylcholinesterase (AChE) that has been covalently inhibited by organophosphate
compounds (OPCs), such as nerve agents and pesticides, has traditionally been reactivated …

Background: Chloroquine (CQ), a classic autophagy inhibitor, is used clinically for malaria
prophylaxis and pulmonary hypertension treatment. The adverse effects of CQ on …

STRESZCZENIE W grudniu 2019 r. w Chinach odnotowano pierwsze przypadki zapalania
płuc spowodowane zakażeniem nieznanym dotychczas koronawirusem, który ze względu …

The Paramyxoviridae family comprises of several genera that contain emerging or re-
emerging threats for human and animal health with no real specific effective treatment …

Anti‐malaria drug, chloroquine, has been reported to be effective against influenza A virus
(IAV) in vitro and used in in‐vivo experiments and clinical trial for prevention or treatment of …

Immunoassay techniques are widely used for drug screening in the fields of forensic
toxicology and emergency medicine, because of their simple procedures and rapid outcome …