Design of novel amidoxime ketolide core and an efficient synthesis of WCK 4763: for treatment of gram-positive pneumococci

S Bhavsar, R Tadiparthi, S Pawar, AK Kayastha… - Medicinal Chemistry …, 2023 - Springer
Ketolides are the next generation macrolides, which shows broad spectrum of activity
against macrolide resistant species, Streptococcus pneumoniae and Streptococcus …

Design and development of efficient synthetic strategies for the chiral synthesis of novel ketolide antibiotic, nafithromycin (WCK 4873)

S Bhavsar, R Tadiparthi, S Gupta, S Pawar, R Yeole… - Chemical Papers, 2023 - Springer
In structure activity relationship-driven novel ketolide drug development program at
Wockhardt, the reaction between racemic 2-[5-(1-bromoethyl)-1, 3, 4-thiadiazol-2-yl] pyridine …