Intrinsic and extrinsic pathways of apoptosis: Role in cancer development and prognosis
Apoptosis, also named programmed cell death, is a fundament process required for
morphogenetic homeostasis during early development and in pathophysiological …
morphogenetic homeostasis during early development and in pathophysiological …
Oxidative stress-modulating drugs have preferential anticancer effects-involving the regulation of apoptosis, DNA damage, endoplasmic reticulum stress, autophagy …
To achieve preferential effects against cancer cells but less damage to normal cells is one of
the main challenges of cancer research. In this review, we explore the roles and …
the main challenges of cancer research. In this review, we explore the roles and …
Metal nanoparticles in cancer: from synthesis and metabolism to cellular interactions
Nanotechnology has encouraged new and amended materials (metal nanoparticles) for
therapeutic applications with specific prominence in healthcare. Metal nanoparticles (NPs) …
therapeutic applications with specific prominence in healthcare. Metal nanoparticles (NPs) …
Molecular targets of celastrol in cancer: Recent trends and advancements
Despite the advancement in the well-equipped and sophisticated laboratories and facilities,
cancer remains to be a major cause of death worldwide. Consequently, further investigation …
cancer remains to be a major cause of death worldwide. Consequently, further investigation …
Apigenin: A natural bioactive flavone-type molecule with promising therapeutic function
There exist overwhelming evidence that plant-derived bioactive flavonoids possess strong
therapeutic activities against cancer, cardiovascular diseases, and age-related …
therapeutic activities against cancer, cardiovascular diseases, and age-related …
In Vitro and In Vivo Biological Activities of Dipicolinate Oxovanadium(IV) Complexes
K Choroba, B Filipe, A Świtlicka… - Journal of Medicinal …, 2023 - ACS Publications
The work is focused on anticancer properties of dipicolinate (dipic)-based vanadium (IV)
complexes [VO (dipic)(N∩ N)] bearing different diimines (2-(1 H-imidazol-2-yl) pyridine, 2-(2 …
complexes [VO (dipic)(N∩ N)] bearing different diimines (2-(1 H-imidazol-2-yl) pyridine, 2-(2 …
Role of reactive oxygen species in cancer progression
Abstract Purpose of Review Although there are significant improvements in diagnosis and
therapeutics tools, cancer remained a major cause of deaths in developing and developed …
therapeutics tools, cancer remained a major cause of deaths in developing and developed …
Quercetin modulates signal transductions and targets non-coding RNAs against cancer development
In recent decades, various investigations have indicated that natural compounds have great
potential in the prevention and treatment of different chronic disorders including different …
potential in the prevention and treatment of different chronic disorders including different …
The neddylation inhibitor MLN4924 inhibits proliferation and triggers apoptosis of oral cancer cells but not for normal cells
YN Chen, YH Chan, JP Shiau… - Environmental …, 2024 - Wiley Online Library
Increased neddylation benefits the survival of several types of cancer cells. The inhibition of
neddylation has the potential to exert anticancer effects but is rarely assessed in oral cancer …
neddylation has the potential to exert anticancer effects but is rarely assessed in oral cancer …
Effect of mono-and dinuclear thiosemicarbazone platinacycles in the proliferation of a colorectal carcinoma cell line
F Reigosa-Chamorro, S Cordeiro, MT Pereira… - Dalton …, 2024 - pubs.rsc.org
Herein, we describe the synthesis and characterization of a series of thiosemicarbazone
platinacycles. Their activity towards HCT116 and A2780 cancer cell lines as well as normal …
platinacycles. Their activity towards HCT116 and A2780 cancer cell lines as well as normal …