Efforts to determine the antibody repertoire encoded by B cells in the blood or lymphoid
organs using high-throughput DNA sequencing technologies have been advancing at an …

The B cell receptor and secreted antibody are at the nexus of humoral adaptive immunity. In
this review, we summarize what is known of the immunoglobulin genes of jawed …

This review describes the extant knowledge on the teleostean mucosal adaptive immune
mechanisms, which is relevant for the development of oral or mucosal vaccines. In the last …

Over the last 30 years, aquaculture has become the fastest growing form of agriculture
production in the world, but its development has been hampered by a diverse range of …

Although mammalian secretory immunoglobulin A (sIgA) targets mucosal pathogens for
elimination, its interaction with the microbiota also enables commensal colonization and …

T and B cell repertoires are collections of lymphocytes, each characterized by its antigen-
specific receptor. We review here classical technologies and analysis strategies developed …

With lymphoid tissue anatomy different than mammals, and diverse adaptations to all
aquatic environments, fish constitute a fascinating group of vertebrate to study the biology of …

Immunoglobulins are glycoproteins which are produced as membrane-bound receptors on
B-cells or in a secreted form, known as antibodies. In teleosts, three immunoglobulin …

Immunoglobulin D (IgD) is an ancient antibody with dual membrane-bound and fluid-phase
antigen receptor functions. The biology of secreted IgD remains elusive. Here, we …

Three different immunoglobulin (Ig) isotypes can be found in teleost fish, IgM, IgD, and the
teleost-specific IgT. IgM is considered to have a systemic activity, and IgT is attributed a …