The presence of disease-specific autoantibody responses and the efficacy of B cell-targeting
therapies in rheumatoid arthritis (RA) indicate a pivotal role for B cells in disease …

Rheumatoid arthritis (RA) is one of the most common autoimmune diseases caused by
abnormal immune activation and immune tolerance. Immunomodulatory cells (ICs) play a …

The mucosal origins hypothesis of rheumatoid arthritis (RA) proposes a central role for
mucosal immune responses in the initiation or perpetuation of the systemic autoimmunity …

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovitis and
destruction of cartilage, promoted by sustained inflammation. However, current treatments …

The procedure to diagnose anemia is time-consuming and resource-intensive due to the
existence of a multitude of symptoms that can be felt physically or seen visually. Anemia also …

Background Rheumatoid arthritis, like many inflammatory diseases, is characterized by
episodes of quiescence and exacerbation (flares). The molecular events leading to flares …

Background Rheumatoid arthritis (RA) is classified as seropositive or seronegative,
depending on the presence/absence of rheumatoid factor (RF), primarily IgM RF, and/or anti …

Individuals with high anti-citrullinated protein antibody (ACPA) titers have an increased risk
of developing rheumatoid arthritis (RA). Although our knowledge of the generation and …

Objective To evaluate patterns of elevations of isotypes of rheumatoid factor (RF) and anti–
citrullinated protein antibodies (ACPAs) pre–rheumatoid arthritis (RA) diagnosis and post …

Since the advent of single-cell RNA sequencing (scRNA-seq) methodology, single-cell
analysis has become a powerful tool for exploration of cellular networks and dysregulated …