Evolution of enzyme superfamilies: comprehensive exploration of sequence–function relationships
The sequence and functional diversity of enzyme superfamilies have expanded through
billions of years of evolution from a common ancestor. Understanding how protein sequence …
billions of years of evolution from a common ancestor. Understanding how protein sequence …
ModBase, a database of annotated comparative protein structure models and associated resources
U Pieper, BM Webb, GQ Dong… - Nucleic acids …, 2014 - academic.oup.com
Abstract ModBase (http://salilab. org/modbase) is a database of annotated comparative
protein structure models. The models are calculated by ModPipe, an automated modeling …
protein structure models. The models are calculated by ModPipe, an automated modeling …
Protein footprinting: Auxiliary engine to power the structural biology revolution
Structural biology is entering an exciting time where many new high-resolution structures of
large complexes and membrane proteins are determined regularly. These advances have …
large complexes and membrane proteins are determined regularly. These advances have …
ModBase, a database of annotated comparative protein structure models, and associated resources
U Pieper, BM Webb, DT Barkan… - Nucleic acids …, 2010 - academic.oup.com
Abstract ModBase (http://salilab. org/modbase) is a database of annotated comparative
protein structure models. The models are calculated by ModPipe, an automated modeling …
protein structure models. The models are calculated by ModPipe, an automated modeling …
Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily
E Akiva, JN Copp, N Tokuriki… - Proceedings of the …, 2017 - National Acad Sciences
Insight regarding how diverse enzymatic functions and reactions have evolved from
ancestral scaffolds is fundamental to understanding chemical and evolutionary biology, and …
ancestral scaffolds is fundamental to understanding chemical and evolutionary biology, and …
Protein similarity networks reveal relationships among sequence, structure, and function within the cupin superfamily
R Uberto, EW Moomaw - PloS one, 2013 - journals.plos.org
The cupin superfamily is extremely diverse and includes catalytically inactive seed storage
proteins, sugar-binding metal-independent epimerases, and metal-dependent enzymes …
proteins, sugar-binding metal-independent epimerases, and metal-dependent enzymes …
[HTML][HTML] Integrative structure modeling of macromolecular assemblies from proteomics data
Proteomics techniques have been used to generate comprehensive lists of protein
interactions in a number of species. However, relatively little is known about how these …
interactions in a number of species. However, relatively little is known about how these …
Characterization of metalloproteins by high-throughput X-ray absorption spectroscopy
High-throughput X-ray absorption spectroscopy was used to measure transition metal
content based on quantitative detection of X-ray fluorescence signals for 3879 purified …
content based on quantitative detection of X-ray fluorescence signals for 3879 purified …
GeMMA: functional subfamily classification within superfamilies of predicted protein structural domains
ABSTRACT GeMMA (Genome Modelling and Model Annotation) is a new approach to
automatic functional subfamily classification within families and superfamilies of protein …
automatic functional subfamily classification within families and superfamilies of protein …
Structural basis for featuring of steroid isomerase activity in alpha class glutathione transferases
K Tars, B Olin, B Mannervik - Journal of molecular biology, 2010 - Elsevier
Glutathione transferases (GSTs) are abundant enzymes catalyzing the conjugation of
hydrophobic toxic substrates with glutathione. In addition to detoxication, human GST A3-3 …
hydrophobic toxic substrates with glutathione. In addition to detoxication, human GST A3-3 …