Improving cancer immunotherapy through nanotechnology

MS Goldberg - Nature Reviews Cancer, 2019 - nature.com
Abstract The 2018 Nobel Prize in Physiology or Medicine was awarded to pioneers in the
field of cancer immunotherapy, as the utility of leveraging a patient's coordinated and …

Nanotechnology for COVID-19: therapeutics and vaccine research

G Chauhan, MJ Madou, S Kalra, V Chopra, D Ghosh… - ACS …, 2020 - ACS Publications
The current global health threat by the novel coronavirus disease 2019 (COVID-19) requires
an urgent deployment of advanced therapeutic options available. The role of …

Polymer nanoparticles deliver mRNA to the lung for mucosal vaccination

A Suberi, MK Grun, T Mao, B Israelow… - Science translational …, 2023 - science.org
An inhalable platform for messenger RNA (mRNA) therapeutics would enable minimally
invasive and lung-targeted delivery for a host of pulmonary diseases. Development of lung …

Proton-driven transformable nanovaccine for cancer immunotherapy

N Gong, Y Zhang, X Teng, Y Wang, S Huo… - Nature …, 2020 - nature.com
Cancer vaccines hold great promise for improved cancer treatment. However, endosomal
trapping and low immunogenicity of tumour antigens usually limit the efficiency of …

[HTML][HTML] Gut microbiota and cardiovascular disease: opportunities and challenges

N Kazemian, M Mahmoudi, F Halperin, JC Wu… - Microbiome, 2020 - Springer
Coronary artery disease (CAD) is the most common health problem worldwide and remains
the leading cause of morbidity and mortality. Over the past decade, it has become clear that …

Designer vaccine nanodiscs for personalized cancer immunotherapy

R Kuai, LJ Ochyl, KS Bahjat, A Schwendeman… - Nature materials, 2017 - nature.com
Despite the tremendous potential of peptide-based cancer vaccines, their efficacy has been
limited in humans. Recent innovations in tumour exome sequencing have signalled the new …

Engineered nanoparticles for drug delivery in cancer therapy

T Sun, YS Zhang, B Pang, DC Hyun… - Nanomaterials and …, 2021 - taylorfrancis.com
In medicine, nanotechnology has sparked a rapidly growing interest as it promises to solve a
number of issues associated with conventional therapeutic agents, including their poor …

Biomimetic nanotechnology toward personalized vaccines

J Zhou, AV Kroll, M Holay, RH Fang… - Advanced …, 2020 - Wiley Online Library
While traditional approaches for disease management in the era of modern medicine have
saved countless lives and enhanced patient well‐being, it is clear that there is significant …

[HTML][HTML] Advanced implications of nanotechnology in disease control and environmental perspectives

P Biswas, SA Polash, D Dey, MA Kaium… - Biomedicine & …, 2023 - Elsevier
Nanotechnology encompasses a wide range of devices derived from biology, engineering,
chemistry, and physics, and this scientific field is composed of great collaboration among …

Synthetic nanoparticles for vaccines and immunotherapy

DJ Irvine, MC Hanson, K Rakhra, T Tokatlian - Chemical reviews, 2015 - ACS Publications
The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …