Principles of odor coding in vertebrates and artificial chemosensory systems

I Manzini, D Schild, C Di Natale - Physiological reviews, 2022 - journals.physiology.org
The biological olfactory system is the sensory system responsible for the detection of the
chemical composition of the environment. Several attempts to mimic biological olfactory …

Odor coding in the mammalian olfactory epithelium

SM Kurian, RG Naressi, D Manoel, AS Barwich… - Cell and Tissue …, 2021 - Springer
Noses are extremely sophisticated chemical detectors allowing animals to use scents to
interpret and navigate their environments. Odor detection starts with the activation of odorant …

Odorant receptor inhibition is fundamental to odor encoding

P Pfister, BC Smith, BJ Evans, JH Brann, C Trimmer… - Current Biology, 2020 - cell.com
Most natural odors are complex mixtures of volatile components, competing to bind odorant
receptors (ORs) expressed in olfactory sensory neurons (OSNs) of the nose. To date …

Olfactory receptor function

I Glezer, B Malnic - Handbook of clinical neurology, 2019 - Elsevier
Olfaction plays a critical role in several aspects of life. Olfactory disorders are very common
in the general population, and can lead to malnutrition, weight loss, food poisoning …

Functional odor classification through a medicinal chemistry approach

E Poivet, N Tahirova, Z Peterlin, L Xu, DJ Zou… - Science …, 2018 - science.org
Crucial for any hypothesis about odor coding is the classification and prediction of sensory
qualities in chemical compounds. The relationship between perceptual quality and …

Assessing the efficacy of eDNA metabarcoding for measuring microbial biodiversity within forest ecosystems

ZS Ladin, B Ferrell, JT Dums, RM Moore, DF Levia… - Scientific Reports, 2021 - nature.com
We investigated the nascent application and efficacy of sampling and sequencing
environmental DNA (eDNA) in terrestrial environments using rainwater that filters through …

E-cigarette Flavors, Sensory Perception, and Evoked Responses

SK Alhadyan, V Sivaraman… - Chemical research in …, 2022 - ACS Publications
The chemosensory experiences evoked by flavors encompass a number of unique
sensations that include olfactory stimuli (smell), gustatory stimuli (taste, ie, salty, sweet, sour …

Introns control stochastic allele expression bias

B Sands, S Yun, AR Mendenhall - Nature Communications, 2021 - nature.com
Monoallelic expression (MAE) or extreme allele bias can account for incomplete penetrance,
missing heritability and non-Mendelian diseases. In cancer, MAE is associated with shorter …

Genetic depletion of class I odorant receptors impacts perception of carboxylic acids

A Cichy, A Shah, A Dewan, S Kaye, T Bozza - Current Biology, 2019 - cell.com
The mammalian main olfactory pathway detects myriad volatile chemicals using> 1,000
odorant receptor (OR) genes, which are organized into two phylogenetically distinct classes …

The role of olfactory genes in the expression of rodent paternal care behavior

TL Rymer - Genes, 2020 - mdpi.com
Olfaction is the dominant sensory modality in rodents, and is crucial for regulating social
behaviors, including parental care. Paternal care is rare in rodents, but can have significant …