Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities

LA Bienvenu, J Noonan, X Wang… - Cardiovascular …, 2020 - academic.oup.com
The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …

Potential therapeutic targets and vaccine development for SARS-CoV-2/COVID-19 pandemic management: a review on the recent update

U Anand, S Jakhmola, O Indari, HC Jha… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly pathogenic
novel virus that has caused a massive pandemic called coronavirus disease 2019 (COVID …

Risk of COVID-19 death in cancer patients: an analysis from Guy's Cancer Centre and King's College Hospital in London

B Russell, CL Moss, V Shah, TK Ko, K Palmer… - British journal of …, 2021 - nature.com
Background Using an updated dataset with more patients and extended follow-up, we
further established cancer patient characteristics associated with COVID-19 death. Methods …

Targeting androgen regulation of TMPRSS2 and ACE2 as a therapeutic strategy to combat COVID-19

Q Deng, R ur Rasool, RM Russell, R Natesan… - IScience, 2021 - cell.com
Epidemiological data showing increased severity and mortality of COVID-19 in men
suggests a potential role for androgen in SARS-CoV-2 infection. Here, we present evidence …

Human genetic basis of coronavirus disease 2019

H Deng, X Yan, L Yuan - Signal transduction and targeted therapy, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) caused by a novel coronavirus, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in considerable …

Loss of mitochondrial membrane potential (ΔΨm) in leucocytes as post-COVID-19 sequelae

KJG Díaz-Resendiz, AB Benitez-Trinidad… - Journal of Leukocyte …, 2022 - academic.oup.com
The mitochondrial membrane potential (Δ Ψ m) is a parameter often used to determine
mitochondrial function; therefore, it can be used to determine the integrity and functionality of …

[HTML][HTML] The sex and gender dimensions of COVID-19: A narrative review of the potential underlying factors

JT Mourosi, S Anwar, MJ Hosen - Infection, Genetics and Evolution, 2022 - Elsevier
Multiple lines of evidence indicate that the male sex is a significant risk factor for severe
disease and mortality due to coronavirus disease 2019 (COVID-19). However, the precise …

Expression of the SARS-CoV-2 receptorACE2 in human heart is associated with uncontrolled diabetes, obesity, and activation of the renin angiotensin system

M Herman-Edelstein, T Guetta, A Barnea… - Cardiovascular …, 2021 - Springer
Background Diabetic and obese patients are at higher risk of severe disease and cardiac
injury in corona virus 2 (SARS-CoV-2) infections. Cellular entry of SARS-CoV-2 is mainly via …

The prevalence, predictors and outcomes of acute liver injury among patients with COVID‐19: A systematic review and meta‐analysis

H Harapan, JK Fajar, S Supriono… - Reviews in medical …, 2022 - Wiley Online Library
The data on the predictors and prognosis of acute liver injury (ALI) among patients in
coronavirus disease 2019 (COVID‐19) patients are limited. The aim of this study was to …

The COVID-19 pandemic—what have urologists learned?

B Ebner, Y Volz, JN Mumm, CG Stief… - Nature Reviews …, 2022 - nature.com
On 11 March 2020, the WHO declared the coronavirus disease 2019 (COVID-19) outbreak a
pandemic and COVID-19 emerged as one of the biggest challenges in public health and …