Synergy and antagonism in natural product extracts: when 1+ 1 does not equal 2
Covering: 2000 to 2019 According to a 2012 survey from the Centers for Disease Control
and Prevention, approximately 18% of the US population uses natural products (including …
and Prevention, approximately 18% of the US population uses natural products (including …
Interactions between natural products—A review
Plant-based natural products have been used as a source for therapeutics since the dawn of
civilization. According to the World Health Organization (WHO), more than 80% of the …
civilization. According to the World Health Organization (WHO), more than 80% of the …
Network-based modeling of herb combinations in traditional Chinese medicine
Traditional Chinese medicine (TCM) has been practiced for thousands of years for treating
human diseases. In comparison to modern medicine, one of the advantages of TCM is the …
human diseases. In comparison to modern medicine, one of the advantages of TCM is the …
Systems pharmacology to reveal multi-scale mechanisms of traditional Chinese medicine for gastric cancer
L Zhang, Y Xiao, R Yang, S Wang, SX Ma, J Liu… - Scientific Reports, 2021 - nature.com
Because of the complex etiology, the treatment of gastric cancer is a formidable challenge
for contemporary medical. The current treatment method focuses on traditional surgical …
for contemporary medical. The current treatment method focuses on traditional surgical …
Network Pharmacology-Based Strategy for the Investigation of the Anti-Obesity Effects of an Ethanolic Extract of Zanthoxylum bungeanum Maxim
Y Wang, SH Yang, K Zhong, T Jiang… - Frontiers in …, 2020 - frontiersin.org
Network pharmacology is considered as the next paradigm in drug discovery. In an era
when obesity has become global epidemic, network pharmacology becomes an ideal tool to …
when obesity has become global epidemic, network pharmacology becomes an ideal tool to …
Systematic elucidation of the mechanism of genistein against pulmonary hypertension via network pharmacology approach
Y Chen, D Chen, S Liu, T Yuan, J Guo, L Fang… - International Journal of …, 2019 - mdpi.com
Numerous studies have shown that genistein has a good therapeutic effect on pulmonary
hypertension (PH). However, there has been no systematic research performed yet to …
hypertension (PH). However, there has been no systematic research performed yet to …
A novel strategy for decoding and validating the combination principles of huanglian jiedu decoction from multi-scale perspective
KX Wang, Y Gao, WX Gong, XF Ye, LY Fan… - Frontiers in …, 2020 - frontiersin.org
Traditional Chinese medicine (TCM) formulas treat complex diseases through combined
botanical drugs which follow specific compatibility rules to reduce toxicity and increase …
botanical drugs which follow specific compatibility rules to reduce toxicity and increase …
Exploring the protective effects and mechanism of crocetin from saffron against NAFLD by network pharmacology and experimental validation
Z Xu, S Lin, J Gong, P Feng, Y Cao, Q Li, Y Jiang… - Frontiers in …, 2021 - frontiersin.org
Background: Non-alcoholic fatty liver disease (NAFLD) is a burgeoning health problem but
no drug has been approved for its treatment. Animal experiments and clinical trials have …
no drug has been approved for its treatment. Animal experiments and clinical trials have …
A network pharmacology study on the molecular mechanisms of FDY003 for breast cancer treatment
HS Lee, IH Lee, K Kang, SI Park… - Evidence‐Based …, 2021 - Wiley Online Library
Herbal medicines have drawn considerable attention with regard to their potential
applications in breast cancer (BC) treatment, a frequently diagnosed malignant disease …
applications in breast cancer (BC) treatment, a frequently diagnosed malignant disease …
Crude polysaccharide from a wild mushroom enhances immune response in murine macrophage cells by TLR/NF-κB pathway
Objective Mushroom crude polysaccharides offer a complete package of various medicinal
activities. In this context, the present study aimed to unveil structural and biomedical …
activities. In this context, the present study aimed to unveil structural and biomedical …