Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis

V Wekker, L Van Dammen, A Koning… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is associated with cardiometabolic
disease, but recent systematic reviews and meta-analyses of longitudinal studies that …

Obesity as a disease

J Upadhyay, O Farr, N Perakakis, W Ghaly… - Medical …, 2018 - medical.theclinics.com
Obesity is a complex, chronic medical condition with a major negative impact on human
health. 1 Over the last 30 years, there has been an exponential growth in the prevalence of …

The interplay between androgens and the immune response in polycystic ovary syndrome

S Shabbir, E Khurram, VS Moorthi, YTH Eissa… - Journal of Translational …, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a metabolic-reproductive-endocrine disorder that,
while having a genetic component, is known to have a complex multifactorial etiology. As …

Overweight and obese but not normal weight women with PCOS are at increased risk of type 2 diabetes mellitus—a prospective, population-based cohort study

MME Ollila, S West… - Human …, 2017 - academic.oup.com
STUDY QUESTION What are the respective roles of polycystic ovary syndrome (PCOS),
long-term weight gain and obesity for the development of prediabetes or Type 2 diabetes …

Dietary α-Linolenic acid-rich flaxseed oil exerts beneficial effects on polycystic ovary syndrome through sex steroid hormones—microbiota—inflammation axis in rats

T Wang, L Sha, Y Li, L Zhu, Z Wang, K Li… - Frontiers in …, 2020 - frontiersin.org
Polycystic ovary syndrome (PCOS) represents a common endocrine—metabolic disorder
disease with chronic low-grade inflammation and alteration of intestinal flora. Serving as …

Metabolic consequences of obesity and insulin resistance in polycystic ovary syndrome: diagnostic and methodological challenges

YM Jeanes, S Reeves - Nutrition research reviews, 2017 - cambridge.org
Women with polycystic ovary syndrome (PCOS) have a considerable risk of metabolic
dysfunction. This review aims to present contemporary knowledge on obesity, insulin …

Role of oxidative stress in obese and nonobese PCOS patients

K Uçkan, H Demir, K Turan, E Sarıkaya… - International journal of …, 2022 - Wiley Online Library
Objective. The aim of this study was to evaluate the relationship between the oxidant‐
antioxidant status, endothelial dysfunction, lipid metabolism, and metabolic syndrome risk in …

Comparison of two insulin sensitizers, metformin and myo-inositol, in women with polycystic ovary syndrome (PCOS)

F Fruzzetti, D Perini, M Russo, F Bucci… - Gynecological …, 2017 - Taylor & Francis
Insulin resistance (IR) plays a pivotal role in PCOS. Insulin-sensitizer agents such as
metformin and inositols have been shown to improve the endocrine and metabolic aspects …

Hormonal changes in PCOS

J Yang, C Chen - Journal of Endocrinology, 2024 - joe.bioscientifica.com
Polycystic ovary syndrome (PCOS) is a common endocrinopathy occurring in reproductive-
age women. Hyperandrogenism, polycystic ovaries, chronic anovulation, and metabolic …

Hormonal alterations in PCOS and its influence on bone metabolism

A Krishnan, S Muthusami - Journal of Endocrinology, 2017 - joe.bioscientifica.com
According to the World Health Organization (WHO) polycystic ovary syndrome (PCOS)
occurs in 4–8% of women worldwide. The prevalence of PCOS in Indian adolescents is …