Bacterial infections are account for the majority of hospital-acquired and community-
acquired infections. The emergency and widespread of drug-resistant pathogens has further …

Isatin, chemically an indole-1 H-2, 3-dione, is recognised as one of the most attractive
therapeutic fragments in drug design and development. The template has turned out to be …

Out of the many heterocycles that exhibit pharmaceutical and therapeutic properties,
benzofurans remain the most eye‐catching to scientists ever since their discovery. From …

Acquired immune deficiency syndrome (AIDS)/human immunodeficiency virus (HIV) is one
of the largest and most devastating public health pandemics throughout the world. The …

The widespread deaths of tuberculosis from many decades demands an urgent need for the
development of novel anti-tubercular scaffolds that are more potent and highly selective with …

Pathogenic bacteria, with their innate resistance to drugs, pose a constant threat to human
health and well-being and put a persistent strain on the health care system. Development of …

A series of benzofuran-isatin hybrids 6a-n and 7a-g linked by alkyl linkers were designed
and synthesized. Among them, hybrids 6a-l and 7a-g were assessed for their in vitro anti …

The purpose of this study was to prepare various novel amide tethered ciprofloxacin-1, 2, 3-
triazole-isatin hybrids 7a-l, and evaluate their in vitro anti-mycobacterial activity as well as …

A new series of benzofuran derivatives have been synthesized by the reaction of substituted
N-(4-aminophenyl)-1-benzofuran-2-carboxamide with substituted aromatic sulfonyl …

The series of new 4-substituted picolinohydrazonamides were synthesized (6-25) and
evaluated for tuberculostatic activity. Compounds having a hydrophilic cyclic amine such as …